Debt - Deerfield Facility Agreement (Details) - USD ($)					1 Months Ended	3 Months Ended		9 Months Ended
	Sep. 01, 2016	Feb. 05, 2016	Nov. 21, 2014	Mar. 20, 2014	Sep. 30, 2016	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015	Feb. 04, 2016	Mar. 17, 2014
Line of Credit Facility [Line Items]
Repayments under lines of credit								$ 110,840,000	$ 110,354,000
Loss on debt extinguishment						$ (9,478,000)	$ 0	(9,478,000)	0
Deerfield
Line of Credit Facility [Line Items]
Maximum borrowing capacity											$ 50,000,000
Transaction fee as percentage of principal amount											2.50%
Line of credit			$ 6,000,000	$ 20,000,000
Net proceeds from initial draw under Facility Agreement				19,500,000
Unamortized debt discount			200,000	$ 500,000
Net proceeds from draw under Facility Agreement			$ 5,900,000
Remaining borrowing capacity					$ 0	0		0
Debt instrument, stated interest rate										8.75%
Repayments under lines of credit	$ 33,500,000
Repayments of lines of credit, principle and accrued interest	27,900,000
Repayments of lines of credit, prepayment of premium	5,600,000
Write off of unamortized expense	3,900,000
Loss on debt extinguishment	$ (9,500,000)
Second amendment with deerfield
Line of Credit Facility [Line Items]
Debt instrument, stated interest rate		14.75%
Portion of interest paid-in-kind, percentage	3.00%	6.00%
Amendment fee amount		$ 600,000
Amendment fee, installment amount		$ 200,000
Initial and draw warrants | Deerfield
Line of Credit Facility [Line Items]
Warrants converted to shares (in shares)					268,614
Expense (income) from change in fair value of warrants						(100,000)	(6,300,000)	400,000	(8,000,000)
Draw warrants | Deerfield
Line of Credit Facility [Line Items]
Maximum borrowing capacity											$ 50,000,000
Exercise price of warrants (dollars per share)			$ 16.68	$ 16.68
Line of credit				$ 20,000,000
Number of warrants issued (in shares)			100,000	333,333
Warrants value			$ 900,000	$ 4,700,000
Draw warrants | Maximum | Deerfield
Line of Credit Facility [Line Items]
Number of securities called by warrants associated with each disbursement borrowing (in shares)											833,333
Initial warrants | Deerfield
Line of Credit Facility [Line Items]
Number of securities called by warrants (in shares)											520,833
Exercise price of warrants (dollars per share)											$ 16.68
Warrant amount reclassified as debt discount			$ 200,000	$ 2,300,000
International operations | Discontinued operations, disposed of by sale
Line of Credit Facility [Line Items]
Interest expense, debt excluding amortization						2,156,000	2,142,000	7,240,000	6,504,000
International operations | Discontinued operations, disposed of by sale | Deerfield facility agreement and amended credit facility
Line of Credit Facility [Line Items]
Interest expense, debt excluding amortization						$ 2,200,000	$ 2,100,000	$ 7,200,000	$ 6,500,000