CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (USD $) In Thousands, except Share data	Total	Scient'x [Member]	Phygen, LLC [Member]	Common stock [Member]	Common stock [Member] Scient'x [Member]	Common stock [Member] Phygen, LLC [Member]	Additional paid-in capital [Member]	Additional paid-in capital [Member] Scient'x [Member]	Additional paid-in capital [Member] Phygen, LLC [Member]	Treasury Stock [Member]	Accumulated other comprehensive income (loss) [Member]	Accumulated deficit [Member]
Balance beginning, value at Dec. 31, 2009	$ 74,829			$ 5			$ 175,021				$ 1,263	$ (101,460)
Balance beginning, shares at Dec. 31, 2009				52,558,000
Stock-based compensation	3,330						3,330
Exercise of stock options, value	213						213
Exercise of stock options, shares				65,000
Repurchase and/or forfeiture of common stock, value	(331)						(331)
Repurchase and/or forfeiture of common stock, shares				(82,000)
Mark-to-market for third party restricted stock	(269)						(269)
Issuance of common stock in connection with Public Offering, net of offering costs, value	43,113			1			43,112
Issuance of common stock for equity offering, shares				9,200,000
Stock options issued in connection with Scient'x acquisition	1,040						1,040
Issuance of common stock for employee stock purchase plan, value	151						151
Issuance of common stock for employee stock purchase plan, shares				56,000
Issuance of common stock for restricted share awards granted to employees, value
Issuance of common stock for restricted share awards granted to employees, shares				121,000
Issuance of common stock in connection with license agreements, value	3,500			1			3,499
Issuance of common stock in connection with license agreements, shares				1,622,000
Issuance of common stock in connection with private placement, net of offering costs, value	6,546						6,546
Issuance of common stock in connection with acquisition		151,639			2			151,637
Issuance of common stock in connection with private placement, net of offering costs, shares				1,592,000
Issuance of common stock in connection with acquisition, shares					23,731,000
Mark to market for shares issued in litigation settlement, value	(399)						(302)			(97)
Mark to market for shares issued in litigation settlement, shares				(19,000)
Issuance of common stock in connection with warrant exercise, value
Issuance of common stock in connection with warrant exercise, shares				196,000
Foreign currency translation adjustments	(2,573)										(2,573)
Net loss	(14,355)											(14,355)
Balance ending, value at Dec. 31, 2010	266,434			9			383,647			(97)	(1,310)	(115,815)
Balance ending, shares at Dec. 31, 2010				89,040,000
Stock-based compensation	2,525						2,525
Exercise of stock options, value	104						104
Exercise of stock options, shares				55,000
Repurchase and/or forfeiture of common stock, value	(193)						(193)
Repurchase and/or forfeiture of common stock, shares				(67,000)
Mark-to-market for third party restricted stock	(100)						(100)
Issuance of warrants in connection with credit facility	99						99
Issuance of common stock for employee stock purchase plan, value	142						142
Issuance of common stock for employee stock purchase plan, shares				63,000
Issuance of common stock for restricted share awards granted to employees, value
Issuance of common stock for restricted share awards granted to employees, shares				271,000
Foreign currency translation adjustments	(1,502)										(1,502)
Net loss	(22,181)											(22,181)
Balance ending, value at Dec. 31, 2011	245,328			9			386,224			(97)	(2,812)	(137,996)
Balance ending, shares at Dec. 31, 2011				89,362,000
Stock-based compensation	2,406						2,406
Exercise of stock options, value	76						76
Exercise of stock options, shares	62,000			62,000
Repurchase and/or forfeiture of common stock, value	(49)						(49)
Repurchase and/or forfeiture of common stock, shares				(115,000)
Shares issued for consulting services, value	1,284						1,284
Shares issued for consulting services, shares				938,000
Issuance of common stock for equity offering, shares				231,000
Issuance of common stock for employee stock purchase plan, value	200						200
Issuance of common stock for employee stock purchase plan, shares				145,000
Issuance of common stock for restricted share awards granted to employees, value
Issuance of common stock for restricted share awards granted to employees, shares				701,000
Issuance of common stock in connection with license agreements, value	250						250
Issuance of common stock in connection with license agreements, shares				139,000
Issuance of common stock in connection with acquisition			8,856			1			8,855
Issuance of common stock in connection with acquisition, shares						5,240,000
Foreign currency translation adjustments	2,924										2,924
Net loss	(15,459)											(15,459)
Balance ending, value at Dec. 31, 2012	$ 245,816			$ 10			$ 399,246			$ (97)	$ 112	$ (153,455)
Balance ending, shares at Dec. 31, 2012				96,703,000