Consolidated Statements of Stockholders' Equity - USD ($)	Total	Rights [Member]	Private placement [Member]	Committed Equity Line [Member]	Common stock [Member]	Common stock [Member] Rights [Member]	Common stock [Member] Private placement [Member]	Common stock [Member] Committed Equity Line [Member]	Additional Paid-in Capital [Member]	Additional Paid-in Capital [Member] Rights [Member]	Additional Paid-in Capital [Member] Private placement [Member]	Additional Paid-in Capital [Member] Committed Equity Line [Member]	Accumulated Deficit [Member]	Series A Preferred Stock [Member]	Series A Preferred Stock [Member] Common stock [Member]	Series A Preferred Stock [Member] Preferred Stock [Member]	Series A Preferred Stock [Member] Additional Paid-in Capital [Member]	Series D Preferred Stock [Member]	Series D Preferred Stock [Member] Common stock [Member]	Series D Preferred Stock [Member] Additional Paid-in Capital [Member]	Series D-1 Preferred Stock [Member]	Series D-1 Preferred Stock [Member] Common stock [Member]	Series D-1 Preferred Stock [Member] Additional Paid-in Capital [Member]	Series E Preferred Stock [Member]	Series E Preferred Stock [Member] Common stock [Member]	Series E Preferred Stock [Member] Additional Paid-in Capital [Member]	Series F Preferred Stock [Member]	Series F Preferred Stock [Member] Common stock [Member]	Series F Preferred Stock [Member] Additional Paid-in Capital [Member]	Series G Preferred Stock [Member]	Series G Preferred Stock [Member] Private placement [Member]	Series G Preferred Stock [Member] Common stock [Member]	Series G Preferred Stock [Member] Additional Paid-in Capital [Member]	Series I Preferred Stock [Member]	Series I Preferred Stock [Member] Common stock [Member]	Series I Preferred Stock [Member] Additional Paid-in Capital [Member]	Series I Exchange Notes [Member]	Series I Exchange Notes [Member] Common stock [Member]	Series I Exchange Notes [Member] Additional Paid-in Capital [Member]	Four Percent Original Issue Discount Senior Secured Convertible Promissory Notes [Member]	Four Percent Original Issue Discount Senior Secured Convertible Promissory Notes [Member] Common stock [Member]	Four Percent Original Issue Discount Senior Secured Convertible Promissory Notes [Member] Additional Paid-in Capital [Member]	October 2016 Convertible Notes [Member]	October 2016 Convertible Notes [Member] Common stock [Member]	October 2016 Convertible Notes [Member] Preferred Stock [Member]	October 2016 Convertible Notes [Member] Additional Paid-in Capital [Member]
Beginning balance (in shares) at Dec. 31, 2014					910,555											212,390
Beginning balance at Dec. 31, 2014	$ 7,664,990				$ 91				$ 306,948,874				$ (299,283,996)			$ 21.24
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of stock (in shares)				842,546.15		415,000	100,000	842,546
Issuance of common stock		$ 2,905,000	$ 2,000,000	$ 2,000,000		$ 42	$ 10	$ 84		$ 2,904,958	$ 1,999,990	$ 1,999,916
Conversion of shares (in shares)					4,775,862									4,367					73,299			115,291		247,879.25	247,879
Conversion of shares	25,557,920				$ 478				25,557,442									$ 813,992	$ 7	$ 813,985	$ 3,169,349	$ 12	$ 3,169,337	$ 745,916	$ 25	$ 745,891
Interest and Dividend Expense paid with Common Stock (in shares)					191,190
Interest and Dividend Expense paid with Common Stock	1,034,535				$ 19				1,034,516
Issuance of Restricted Stock (in shares)					12,918
Issuance of Restricted Stock	0				$ 1				(1)
Common stock issued to Placement Agent (in shares)					6,610
Common Stock Issued to Placement Agent	108,980				$ 1				108,979
Commitment Shares (in shares)					43,000
Commitment Shares	54,000				$ 4				53,996
Common shares issued in payment of consulting expenses (in shares)					25,694
Common shares issued in payment of consulting expenses	89,999				$ 3				89,996
Stock based compensation	856,811								856,811
Conversion of October 2016 Convertible Notes into Common Shares, plus make-whole	1,375,000								1,375,000
Net loss	(45,797,798)												(45,797,798)
Ending balance (in shares) at Dec. 31, 2015					7,759,844											212,390
Ending balance at Dec. 31, 2015	2,578,694				$ 777				347,659,690				(345,081,794)			$ 21.24
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of stock (in shares)				525,453.85		2,052,865		525,454																							1,096
Issuance of common stock		$ 1,347,000		$ 1,056,147		$ 205		$ 52		$ 1,346,795		$ 1,056,095
Conversion of shares (in shares)					48,993										6,942,936	(46,849)								41,895,161	41,895,161			113,059,991				234,409,413			6,988,353			14,816,862			64,000,000			42,857,508	(40,497)
Conversion of shares	58,823				$ 5				58,818					$ 222,789	$ 694	$ (4)	$ 222,099							$ 3,418,221	$ 4,189	$ 3,414,032	$ 9,931,454	$ 11,306	$ 9,920,148	$ 1,496,396		$ 23,441	$ 1,472,955	$ 2,533,417	$ 699	$ 2,532,718	$ 160,826	$ 1,481	$ 159,345	$ 251,680	$ 6,400	$ 245,280	$ 177,570	$ 4,286	$ (4)	$ 173,288
Interest and Dividend Expense paid with Common Stock (in shares)					18,575,710
Interest and Dividend Expense paid with Common Stock	256,780				$ 1,858				254,922
Issuance of Restricted Stock (in shares)					183,230
Issuance of Restricted Stock	0				$ 18				(18)
Commitment Shares (in shares)					107,000
Commitment Shares	0				$ 11				(11)
Stock based compensation	888,348								888,348
Conversion of October 2016 Convertible Notes into Common Shares, plus make-whole	481,561								481,561
Net loss	(38,850,782)												(38,850,782)
Ending balance (in shares) at Dec. 31, 2016					554,223,320											125,044
Ending balance at Dec. 31, 2016	$ (13,991,076)				$ 55,422				$ 369,886,065				$ (383,932,576)			$ 13