Equity Incentive Plans - Summary of Stock Option Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	12 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Shares
Options outstanding beginning balance	2,278,789
Options exercised	(107,623)
Options cancelled or expired	(4,291)
Options outstanding ending balance	2,166,875	2,278,789
Options exercisable	1,778,867
Weighted Average Exercise Price
Options outstanding beginning balance	$ 33.52
Options exercised	21.20
Options cancelled or expired	111.83
Options outstanding ending balance	33.98	$ 33.52
Options exercisable	$ 28.90
Weighted Average Remaining Contractual Life (in Years)
Options outstanding	6 years 29 days	6 years 3 months 18 days
Options exercisable	5 years 9 months 21 days
Aggregate Intrinsic Value
Options outstanding	$ 141,996	$ 217,824
Options exercisable	$ 125,598