Shareholders' Equity - Summary of Changes of Shareholders' Equity (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Class Of Stock [Line Items]
Beginning balance	$ 1,026,454	$ 1,080,160
Exercise of stock options	$ 2,281	5,529
Exercise of stock options, Shares	107,623
Stock-based compensation cost	$ 33,371	19,127
Shares issued under employee stock purchase plan	8,006	7,088
Gain (Loss) on translation adjustment	(1,347)	(390)
Net loss	(32,557)	(30,068)
Ending balance	1,036,208	1,081,446
Common Stock
Class Of Stock [Line Items]
Beginning balance	$ 9	$ 9
Beginning balance, Shares	87,086,665	85,057,727
Exercise of stock options, Shares	107,623	296,226
Vesting of restricted stock units and performance share units	466,497	346,008
Shares issued under employee stock purchase plan, Shares	85,926	60,064
Ending balance	$ 9	$ 9
Ending balance, Shares	87,785,002	85,760,025
Common Stock | Performance Share Units
Class Of Stock [Line Items]
Vesting of restricted stock units and performance share units	38,291
Additional Paid-In Capital
Class Of Stock [Line Items]
Beginning balance	$ 1,732,742	$ 1,648,741
Exercise of stock options	2,281	5,529
Stock-based compensation cost	33,371	19,127
Shares issued under employee stock purchase plan	8,006	7,088
Ending balance	1,776,400	1,680,485
Accumulated Other Comprehensive Income (Loss)
Class Of Stock [Line Items]
Beginning balance	(3,428)	(1,339)
Gain (Loss) on translation adjustment	(1,347)	(390)
Ending balance	(4,775)	(1,729)
Accumulated Deficit
Class Of Stock [Line Items]
Beginning balance	(702,869)	(567,251)
Net loss	(32,557)	(30,068)
Ending balance	$ (735,426)	$ (597,319)