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Equity Incentive Plans - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Millions
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Shares subject to outstanding awards 5,483,891   5,884,742
Total intrinsic value of options exercised $ 36.8 $ 109.5  
Weighted average grant date fair value of options granted $ 28.99 $ 17.93  
Number of shares, vested 585,475    
Number of options unvested 2,486,593    
Contractual life 10 years    
Expected term 6 years 6 years  
Employees      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Stock options, average vesting term 4 years    
Expected term 6 years    
Non Employee Directors      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Stock options, average vesting term 1 year    
Expected term 5 years    
Stock Options      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total unrecognized compensation expense related to stock options $ 31.9    
Unrecognized compensation expense expected to be recognized over weighted average period 2 years 7 months 6 days    
Stock Options | Employees      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Stock options vesting period 4 years    
Stock Options | Non Employee Directors      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Stock options vesting period 1 year    
Restricted Stock Units (RSUs)      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Unrecognized compensation expense expected to be recognized over weighted average period 3 years 6 months    
Total unrecognized compensation expense expected to be recognized $ 123.9    
Restricted Stock Units (RSUs) | Employees      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Stock options vesting period 4 years    
Restricted Stock Units (RSUs) | Non Employee Directors      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Stock options vesting period 1 year    
2018 Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of shares of common stock reserved for issuance 5,315,780    
Automatically increase percentage of aggregate number of shares of common stock outstanding 5.00%    
Shares subject to outstanding awards 3,540,159    
Shares available for future issuance 9,204,822    
2006 Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Shares subject to outstanding awards 4,154,956    
2018 Employee Stock Purchase Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of shares of common stock reserved for issuance 996,709    
Total unrecognized compensation expense related to stock options $ 1.3    
Contractual life 10 years    
Expected term 6 months 6 months  
Initial offering period June 15, 2018    
Description of offering period for ESPP The first offering period began on June 15, 2018 and ended on January 31, 2019. Subsequent offering periods begin on August 1 and February 1 (or such other date determined by our Board of Directors or our Compensation and Leadership Development Committee).    
Description of purchase price for shares of common stock purchased under ESPP The purchase price for shares of common stock purchased under the ESPP is 85% of the lesser of the fair market value of the Company’s common stock on (i) the first day of the applicable offering period or (ii) the last day of the purchase period in the applicable offering period.    
Percentage of purchase price for shares of common stock under fair value market 85.00%    
Employee stock purchase plan number of shares initially authorized 10,102,525    
2018 Employee Stock Purchase Plan | Minimum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Automatically increase percentage of aggregate number of shares of common stock outstanding 1.00%    
Percentage of payroll deduction on eligible compensation 1.00%    
Increase of common stock capital shares reserved for future issuance in each of calendar year 1,000,000    
2018 Employee Stock Purchase Plan | Maximum      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Percentage of payroll deduction on eligible compensation 15.00%    
Employee Stock Purchase Plan      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Number of shares of common stock reserved for issuance 1,850,081    
Common stock, shares purchased 81,894