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Equity Incentive Plans - Summary of Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2018
Dec. 31, 2017
Shares    
Options outstanding as of January 1, 2018 10,727,125  
Options granted 2,547,028  
Options exercised (1,131,716)  
Options cancelled (637,173)  
Options expired (138,160)  
Options outstanding as of September 30, 2018 11,367,104 10,727,125
Options exercisable as of September 30, 2018 6,597,314  
Weighted Average Exercise Price    
Options outstanding as of January 1, 2018 $ 9.94  
Options granted 19.50  
Options exercised 8.14  
Options cancelled 14.10  
Options expired 11.15  
Options outstanding as of September 30, 2018 12.02 $ 9.94
Options exercisable as of September 30, 2018 $ 8.58  
Weighted Average Remaining Contractual Life (Years)    
Options outstanding 6 years 11 months 19 days 7 years
Options exercisable as of September 30, 2018 5 years 7 months 20 days  
Aggregate Intrinsic Value    
Options outstanding $ 260,474 $ 71,430
Options exercisable as of September 30, 2018 $ 173,829