SCHEDULE 13G 0001952100 XXXXXXXX LIVE Common Stock, $0.00001 par value per share 02/27/2025 0001347858 22nd Century Group, Inc. 90137F400 321 Farmington Road Mocksville NC 27028 Rule 13d-1(c) JOSEPH REDA X1 88237.00 73447.00 88237.00 73447.00 161684.00 N 8.5 IN (1) Based on 1,893,361 shares of Common Stock of the Issuer outstanding as verified with the Issuer on February 28, 2025. SEG OPPORTUNITY FUND, LLC NY 0.00 73447.00 0.00 73447.00 0.00 N 3.8 OO (1) Based on 1,893,361 shares of Common Stock of the Issuer outstanding as verified with the Issuer on February 28, 2025. 22nd Century Group, Inc. 321 Farmington Road Mocksville, North Carolina 27028 This statement is jointly filed by and on behalf of each of Joseph Reda and SEG Opportunity Fund, LLC, a New York limited liability company ("SEG", and together with Mr. Reda, "Reporting Persons"). Mr. Reda is the manager of, and may be deemed to beneficially own securities beneficially owned by, SEG. SEG is the record and direct beneficial owner of the shares of Common Stock of the Issuer covered by this statement. Each Reporting Person declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, the beneficial owner of any securities covered by this statement. Each Reporting Person may be deemed to be a member of a group with respect to the Issuer or securities of the Issuer for the purpose of Section 13(d) or 13(g) of the Act. Each of the Reporting Persons declares that neither the filing of this statement nor anything herein shall be construed as an admission that such person is, for the purpose of Section 13(d) or 13(g) of the Act or any other purpose, (i) acting (or has agreed or is agreeing to act together with any other person) as a partnership, limited partnership, syndicate, or other group for the purpose of acquiring, holding, or disposing of securities of the Issuer or otherwise with respect to the Issuer or any securities of the Issuer or (ii) a member of any group with respect to the Issuer or any securities of the Issuer. The address of the principal business office of each of the Reporting Persons is 1 Wolfs Lane Suite 316 Pelham, NY 10803 Joseph Reda is a citizen of the United States. SEG is a New York limited liability company. Y See Item 9 on the cover pages(s) hereto. See Item 11 on the cover page(s) hereto. See Item 5 on the cover pages hereto. See Item 6 on the cover pages hereto. See Item 7 on the cover pages hereto. See Item 8 on the cover pages hereto. Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. JOSEPH REDA /s/ Joseph Reda 02/28/2025 SEG OPPORTUNITY FUND, LLC /s/ Joseph Reda 02/28/2025 99.1 Joint Filing Agreement (filed herewith).