X0306 4 2017-10-27 0 0001437786 Immune Design Corp. IMDZ 0001347769 COLUMN GROUP L P 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001614627 COLUMN GROUP GP, LP 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001600420 COLUMN GROUP II, LP 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001645333 Column Group II GP, LP 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001707230 PONOI CAPITAL, LP 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001720702 Ponoi Management, LLC 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001182464 GOEDDEL DAVID V 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001614186 Kutzkey Tim 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 Common Stock 2017-10-27 4 P 0 2681000 4.10 A 6642942 D Reflects the purchase of shares by Ponoi Capital, LP ("Ponoi LP") in the follow-on offering of Common Stock of Immune Design Corp. that closed on October 27, 2017. Includes shares directly held by Ponoi LP, The Column Group II, LP ("TCG II LP") and The Column Group, LP ("TCG LP"). The Column Group II GP, LP ("TCG II GP"), as the general partner of TCG II LP, has voting and dispositive power with respect to certain of the shares. The Column Group GP, LP ("TCG GP"), as the general partner of TCG LP, has voting and dispositive power with respect to certain of the shares. Ponoi Management, LLC ("Ponoi LLC"), as the general partner of Ponoi LP, has voting and dispositive power with respect to certain of the shares. (Continued From Footnote 2) The individual managing partners of both TCG II GP and TCG GP are Peter Svennilson and David Goeddel, who may be deemed to have shared voting and dispositive power with respect to the shares owned by TCG II LP and TCG LP. The individual managing partners of Ponoi LLC are Peter Svennilson, David Goeddel and Tim Kutzkey, who may be deemed to have shared voting and dispositive power with respect to the shares owned by Ponoi LP. Each individual managing partner disclaims beneficial ownership of the shares, except to the extent of his pecuniary interest in such shares. THE COLUMN GROUP, LP, /s/ Peter Svennilson, Name: Peter Svennilson, Managing Partner 2017-10-30 THE COLUMN GROUP GP, LP, /s/ Peter Svennilson, Name: Peter Svennilson, Managing Partner 2017-10-30 THE COLUMN GROUP II, LP, /s/ Peter Svennilson, Name: Peter Svennilson, Managing Partner 2017-10-30 THE COLUMN GROUP II GP, LP, /s/ Peter Svennilson, Name: Peter Svennilson, Managing Partner 2017-10-30 PONOI CAPITAL, LP, /s/ Peter Svennilson, Name: Peter Svennilson, Managing Partner 2017-10-30 PONOI MANAGEMENT, LLC, /s/ Peter Svennilson, Name: Peter Svennilson, Managing Partner 2017-10-30 /s/ David V. Goeddel, Name: David V. Goeddel 2017-10-30 /s/ Tim Kutzkey, Name: Tim Kutzky 2017-10-30