CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Income Statement [Abstract]
Revenues	$ 0	$ 0	$ 0	$ 0
Costs and Expenses:
Research and development	26,611	19,525	47,786	37,723
Selling, general and administrative	10,249	7,394	16,624	12,000
Loss from Operations	(36,860)	(26,919)	(64,410)	(49,723)
Other Loss
Interest and investment expense, net	(1,673)	(5,207)	(8,709)	(9,524)
Debt conversion expense	0	0	(25,615)	0
Change in fair value of derivative instruments-warrants	(23)	(1,542)	237	(1,810)
Total Other Loss	(1,696)	(6,749)	(34,087)	(11,334)
Net Loss	$ (38,556)	$ (33,668)	$ (98,497)	$ (61,057)
Weighted Average Common Shares Outstanding
Basic and Diluted (in shares)	168,127,144	100,343,637	143,017,970	98,523,696
Net Loss per Common Share, Basic and Diluted
Net Loss per Common Share, Basic and Diluted (in dollars per share)	$ (0.23)	$ (0.34)	$ (0.69)	$ (0.62)