XML 25 R14.htm IDEA: XBRL DOCUMENT v3.5.0.2
Research and Development Expense
6 Months Ended
Jun. 30, 2016
Research and Development [Abstract]  
Research and Development Expense
Research and Development Expense

Research and development costs include expenditures in connection with an in-house research and development laboratory, salaries and staff costs, application and filing for regulatory approval of proposed products, regulatory and scientific consulting fees, as well as contract research, patient costs, drug formulation and tableting, data collection, monitoring, and clinical insurance.

In accordance with FASB ASC Topic 730-10-55, Research and Development, Synergy recorded prepaid research and development costs of approximately $3.9 million as of June 30, 2016 and $3.1 million as of December 31, 2015, for nonrefundable advances for production of drug substance and analytical testing services for its drug candidates. In accordance with this guidance, Synergy expenses these costs when drug compound is delivered and services are performed.