CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Income Statement [Abstract]
Revenues	$ 0	$ 0
Costs and Expenses:
Research and development	21,175	18,198
Selling, general and administrative	6,375	4,606
Loss from Operations	(27,550)	(22,804)
Other Loss
Interest and investment expense, net	(7,036)	(4,317)
Debt conversion expense	(25,615)	0
Change in fair value of derivative instruments-warrants	260	(268)
Total Other Loss	(32,391)	(4,585)
Net Loss	$ (59,941)	$ (27,389)
Weighted Average Common Shares Outstanding
Basic and Diluted (in shares)	117,626,669	96,683,525
Net Loss per Common Share, Basic and Diluted
Net Loss per Common Share, Basic and Diluted (in dollars per share)	$ (0.51)	$ (0.28)