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Carrying amount, as of the balance sheet date, of payments made in advance for research and development costs, which will be charged against earnings within one year or the normal operating cycle, if longer.

+ References

No definition available.

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- Definition

For an unclassified balance sheet, a valuation allowance for receivables due a company that are expected to be uncollectible.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 310
-SubTopic 10
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- Definition

Amount of loans and leases that have been written off from both loan receivables and allowance reserve for credit loss.

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-Publisher FASB
-Name Accounting Standards Codification
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-Section 50
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-Subparagraph (SX 210.9-03.7(d))
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- Definition

Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented.

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-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
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- Definition

Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.

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- Definition

For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
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- Definition

Face (par) amount of debt instrument at time of issuance.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 55
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- References

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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No definition available.

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Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

+ References

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Basis of Presentation, Accounting Policies and Going Concern (Details) - USD ($)	9 Months Ended	12 Months Ended
	Sep. 30, 2017	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014	Nov. 03, 2014
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Cash and cash equivalents		$ 136,986,000	$ 82,387,000	$ 61,653,000	$ 146,470,000
Allowance for loan and lease losses, write-offs	$ 0
Allowance for doubtful accounts receivable	$ 0
Property, Plant and Equipment [Line Items]
Prepaid research and development costs		$ 72,000	$ 33,000
Total shares issuable upon exercise or conversion (in shares)		58,425,077	36,347,633	76,809,137
Stock Options
Property, Plant and Equipment [Line Items]
Total shares issuable upon exercise or conversion (in shares)		29,868,291	27,867,171	20,953,375
Warrants
Property, Plant and Equipment [Line Items]
Total shares issuable upon exercise or conversion (in shares)		22,575,114	919,690	4,726,823
Senior Convertible Notes
Property, Plant and Equipment [Line Items]
Total shares issuable upon exercise or conversion (in shares)		5,981,672	7,560,772	51,128,939
Convertible Senior Notes Due 2019
Property, Plant and Equipment [Line Items]
Aggregate principal amount		$ 18,603,000	$ 23,500,000.0	$ 159,000,000		$ 200,000,000
Number of shares issued on conversion of debt (in shares)		5,981,672	7,560,772	51,128,939
Minimum \| Furniture and equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, useful life		2 years
Maximum \| Furniture and equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, useful life		5 years
Three Largest Customer \| Customer Concentration Risk \| Accounts Receivable
Property, Plant and Equipment [Line Items]
Concentration risk, percentage		97.00%
AmerisourceBergen \| Customer Concentration Risk \| Accounts Receivable
Property, Plant and Equipment [Line Items]
Concentration risk, percentage		39.00%
McKesson Corporation \| Customer Concentration Risk \| Accounts Receivable
Property, Plant and Equipment [Line Items]
Concentration risk, percentage		31.00%
Cardinal Health \| Customer Concentration Risk \| Accounts Receivable
Property, Plant and Equipment [Line Items]
Concentration risk, percentage		25.00%