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Business Overview (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Feb. 28, 2017
Feb. 06, 2017
Jan. 31, 2017
Mar. 18, 2016
Mar. 31, 2017
Nov. 30, 2016
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Jun. 30, 2016
Mar. 31, 2016
Jun. 30, 2017
Jun. 30, 2016
Dec. 31, 2015
Nov. 03, 2014
Organization, Consolidation and Presentation of Financial Statements [Abstract]                              
Net cash (used in) operating activities                       $ (120,772,000) $ (60,127,000)    
Cash and cash equivalents             $ 81,960,000   $ 82,387,000 $ 141,219,000   81,960,000 141,219,000 $ 61,653,000  
Net loss             (73,889,000)     (38,556,000)   (138,493,000) (98,497,000)    
Income (loss) from operations             (73,583,000)     (36,860,000)   (136,310,000) (64,410,000)    
Working capital             59,400,000         59,400,000      
Subsidiary, Sale of Stock [Line Items]                              
Proceeds of sale of common stock                       121,951,000 89,845,000    
Payment for indenture consent $ 1,600,000                            
Debt conversion amount                       4,912,000 82,274,000    
Debt conversion expense             0 $ 1,209,000   $ 0   $ 1,209,000 $ 25,615,000    
Common Shares                              
Organization, Consolidation and Presentation of Financial Statements [Abstract]                              
Shares sold in private placement (in shares)                       20,325,204      
Subsidiary, Sale of Stock [Line Items]                              
Debt conversion expense (in shares)               200,000       212,800      
Convertible Senior Notes Due 2019                              
Subsidiary, Sale of Stock [Line Items]                              
Debt conversion amount       $ 79,800,000 $ 4,900,000 $ 55,700,000   $ 4,911,000 $ 55,668,000   $ 79,829,000        
Number of shares issued on conversion of debt (in shares)       35,300,000 1,800,000 20,500,000                  
Debt conversion per original conversion price (in shares)         1,600,000       2,600,000   9,600,000        
Conversion price (in dollars per share)       $ 3.11                     $ 3.11
Aggregate principal amount             $ 18,600,000         $ 18,600,000     $ 200,000,000
Debt conversion expense                 $ 14,500,000   $ 25,600,000        
Public Stock Offering                              
Organization, Consolidation and Presentation of Financial Statements [Abstract]                              
Shares sold in private placement (in shares)     20,325,204                        
Shares issued (in dollars per share)     $ 6.15                        
Subsidiary, Sale of Stock [Line Items]                              
Proceeds of sale of common stock   $ 121,600,000