Basis of Presentation, Accounting Policies and Going Concern (Tables)

12 Months Ended

Dec. 31, 2016

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Schedule of antidilutive securities excluded from computation of earnings per share

The following table sets forth potential common shares issuable upon the exercise of outstanding options, the exercise of warrants, and the conversion of the Senior Convertible Notes, all of which have been excluded from the computation of diluted weighted average shares outstanding as they would be anti-dilutive, including the impact on dilutive net loss per share of in-the-money warrants as per ASC 260-10-45-35 through ASC 260-10-45-37:

	Year Ended December 31, 2016	Year Ended December 31, 2015	Year Ended December 31, 2014
Stock Options	27,867,171	20,953,375	16,567,020
Warrants	919,690	4,726,823	5,647,203
Senior Convertible Notes	7,560,772	51,128,939	64,308,680
Total shares issuable upon exercise or conversion	36,347,633	76,809,137	86,522,903