CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015
Cash Flows From Operating Activities:
Net loss	$ (138,740)	$ (87,053)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	193	103
Amortization of deferred debt costs	4,658	4,060
Stock-based compensation expense	8,494	7,724
Value of common stock issued for patent license	0	71
Accretion of discount/premium on available for sale securities	0	(97)
Change in fair value of derivative instruments—warrants	(151)	364
Common stock issued for interest on Notes	2,445	0
Debt conversion expense	25,615	0
Changes in operating assets and liabilities:
Security deposit	0	(56)
Accounts payable and accrued expenses	3,452	(1,042)
Prepaid expenses and other current assets	1,561	2,781
Accrued interest expense on senior convertible notes	486	2,470
Total Adjustments	46,753	16,378
Net Cash used in Operating Activities	(91,987)	(70,675)
Cash Flows From Investing Activities:
Net sales (purchases) of available-for-sale securities	50,097	(50,188)
Additions to property and equipment	(297)	(50)
Net Cash provided by (used in) Investing Activities	49,800	(50,238)
Cash Flows From Financing Activities:
Proceeds of sale of common stock	89,845	14,672
Fees and expenses — note conversions	(434)	0
Fees and expenses — sale of common stock	0	(404)
Proceeds from exercise of warrants	0	1,012
Proceeds from exercise of stock options	213	1,079
Net Cash provided by Financing Activities	89,624	16,359
Net increase (decrease) in cash and cash equivalents	47,437	(104,554)
Cash and cash equivalents at beginning of period	61,653	146,470
Cash and cash equivalents at end of period	109,090	41,916
Supplementary disclosure of cash flow information:
Cash paid for interest on senior convertible notes	2,969	7,416
Cash paid for taxes	45	258
Supplementary disclosure of non-cash investing and financing activities:
Conversion of senior convertible notes to Synergy Common Stock	$ 82,274	$ 40,989