CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Income Statement [Abstract]
Revenues	$ 0	$ 0	$ 0	$ 0
Costs and Expenses:
Research and development	24,610	20,424	72,396	58,147
Selling, general and administrative	13,872	2,728	30,497	14,727
Loss from Operations	(38,482)	(23,152)	(102,893)	(72,874)
Other Loss
Interest and investment expense, net	(1,674)	(4,291)	(10,383)	(13,815)
Debt conversion expense	0	0	(25,615)	0
Change in fair value of derivative instruments-warrants	(87)	1,446	151	(364)
Total Other Loss	(1,761)	(2,845)	(35,847)	(14,179)
Net Loss	$ (40,243)	$ (25,997)	$ (138,740)	$ (87,053)
Weighted Average Common Shares Outstanding
Basic and Diluted (in shares)	179,786,580	111,328,339	155,410,353	102,838,814
Net Loss per Common Share, Basic and Diluted
Net Loss per Common Share, Basic and Diluted (in dollars per share)	$ (0.22)	$ (0.23)	$ (0.89)	$ (0.85)