<SEC-DOCUMENT>0001104659-17-052471-index.html : 20170817
<SEC-HEADER>0001104659-17-052471.hdr.sgml : 20170817
<ACCEPTANCE-DATETIME>20170817163353
ACCESSION NUMBER:		0001104659-17-052471
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20170817
DATE AS OF CHANGE:		20170817
EFFECTIVENESS DATE:		20170817

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SYNERGY PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001347613
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				330505269
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-220016
		FILM NUMBER:		171039014

	BUSINESS ADDRESS:	
		STREET 1:		420 LEXINGTON AVENUE
		STREET 2:		SUITE 2012
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10170
		BUSINESS PHONE:		212-297-0010

	MAIL ADDRESS:	
		STREET 1:		420 LEXINGTON AVENUE
		STREET 2:		SUITE 2012
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10170

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Synergy Pharmaceuticals, Inc.
		DATE OF NAME CHANGE:	20080812

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PAWFECT FOODS INC
		DATE OF NAME CHANGE:	20051221
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>a17-20288_1s8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: a17-20288_1s8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>a17-20288_1ex5d1.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: a17-20288_1ex5d1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>3
<FILENAME>a17-20288_1ex23d2.htm
<DESCRIPTION>EX-23.2
<TEXT>
Document 3 - file: a17-20288_1ex23d2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g202881kgi001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: g202881kgi001.jpg

</DOCUMENT>
</SEC-DOCUMENT>