Commitments and Contingencies (Details) (USD $)	12 Months Ended			0 Months Ended			6 Months Ended
	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012	Jan. 07, 2015 multiplier	Jan. 01, 2015	Jun. 30, 2014	Dec. 31, 2014
Commitments and contingencies
Rent expense	$ 651,000	$ 575,000	$ 300,000
Employment and Consulting Agreements | Gary S. Jacob, Ph.D.
Commitments and contingencies
Current base salary per year				500,000
Renewal period				1 year
Multiplier percentage of enterprise value of joint venture or license fees of an out license for bonus realization				0.50%
Period after the merger or sale when enterprise value equals or exceed specified amount				12 months
Multiplier percentage of enterprise value on fulfillment of specified criteria for bonus receipt				2.50%
Multiplier percentage of enterprise value on fulfillment of specified criteria for bonus receipt in scenario 2				3.50%
Period preceding termination for which average monthly base salary paid or accrued will be paid to individual as severance payment				3 months
Expense compensation multiplier of the sum of average base salary during the specified period preceding the termination				12
Period preceding the termination for which an average base salary will be paid to individual as expense compensation				3 months
Period following the termination date for extension of the exercise period of options				10 years
Period following termination for which cost of medical insurance will be paid				12 months
Lump sum payment on employment termination upon change of control	2,286,000						2,286,000
Employment and Consulting Agreements | Gary S. Jacob, Ph.D. | Maximum
Commitments and contingencies
Cash bonus, as a percentage of base pay per year based on meeting certain performance objectives and bonus criteria				50.00%
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus (as a percent)				20.00%
Employment and Consulting Agreements | Gary S. Jacob, Ph.D. | Minimum
Commitments and contingencies
Enterprise value of the joint venture for receipt of realization bonus				250,000,000
License fees contracted to receive receipt of realization bonus				50,000,000
Enterprise value at the time of the merger or sale for receipt of bonus				400,000,000
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus (as a percent)				20.00%
Enterprise value at the time of merger or sale or twelve months after merger or sale for receipt of bonus				250,000,000
Enterprise value at the time of the merger or sale for receipt of bonus in Scenario 2				1,000,000,000
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus in scenario 2 (as a percent)				20.00%
Employment and Consulting Agreements | Gabriele M. Cerrone
Commitments and contingencies
Current base salary per year				425,000
Renewal period				1 year
Multiplier percentage of enterprise value of joint venture or license fees of an out license for bonus realization				0.50%
Period after the merger or sale when enterprise value equals or exceed specified amount				12 months
Multiplier percentage of enterprise value on fulfillment of specified criteria for bonus receipt				2.50%
Multiplier percentage of enterprise value on fulfillment of specified criteria for bonus receipt in scenario 2				3.50%
Period preceding termination for which average monthly base salary paid or accrued will be paid to individual as severance payment				3 months
Expense compensation multiplier of the sum of average base salary during the specified period preceding the termination				12
Period preceding the termination for which an average base salary will be paid to individual as expense compensation				3 months
Period following the termination date for extension of the exercise period of options				10 years
Period following termination for which cost of medical insurance will be paid				12 months
Lump sum payment on employment termination upon change of control	1,942,500						1,942,500
Severance payment multiplier of the average monthly base compensation paid or accrued during specified period preceding the termination				12
Employment and Consulting Agreements | Gabriele M. Cerrone | Maximum
Commitments and contingencies
Cash bonus, as a percentage of base pay per year based on meeting certain performance objectives and bonus criteria				50.00%
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus (as a percent)				20.00%
Employment and Consulting Agreements | Gabriele M. Cerrone | Minimum
Commitments and contingencies
Enterprise value of the joint venture for receipt of realization bonus				250,000,000
License fees contracted to receive receipt of realization bonus				50,000,000
Enterprise value at the time of the merger or sale for receipt of bonus				400,000,000
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus (as a percent)				20.00%
Enterprise value at the time of merger or sale or twelve months after merger or sale for receipt of bonus				250,000,000
Enterprise value at the time of the merger or sale for receipt of bonus in Scenario 2				1,000,000,000
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus in scenario 2 (as a percent)				20.00%
Employment and Consulting Agreements | Bernard F. Denoyer
Commitments and contingencies
Current base salary per year					240,000
Period preceding termination for which average monthly base salary paid or accrued will be paid to individual as severance payment	3 months
Period following the termination date for extension of the exercise period of options	10 years
Period following termination for which cost of medical insurance will be paid	12 months
Lump sum payment on employment termination upon change of control	341,000						341,000
Renewal term of agreement	1 year
Severance payment multiplier of the average monthly base compensation paid or accrued during specified period preceding the termination	12
Employment and Consulting Agreements | Bernard F. Denoyer | Maximum
Commitments and contingencies
Cash bonus, percentage of base salary at the discretion of the Compensation Committee of the Board of Directors	25.00%						25.00%
Employment and Consulting Agreements | Kunwar Shailubhai
Commitments and contingencies
Current base salary per year					330,000
Multiplier percentage of enterprise value of joint venture or license fees of an out license for bonus realization				0.20%
Period after the merger or sale when enterprise value equals or exceed specified amount				12 months
Multiplier percentage of enterprise value on fulfillment of specified criteria for bonus receipt				1.00%
Multiplier percentage of enterprise value on fulfillment of specified criteria for bonus receipt in scenario 2				1.17%
Period preceding termination for which average monthly base salary paid or accrued will be paid to individual as severance payment				3 months
Period following the termination date for extension of the exercise period of options				10 years
Period following termination for which cost of medical insurance will be paid				12 months
Lump sum payment on employment termination upon change of control				692,000
Renewal term of agreement				1 year
Severance payment multiplier of the average monthly base compensation paid or accrued during specified period preceding the termination				12
Employment and Consulting Agreements | Kunwar Shailubhai | Maximum
Commitments and contingencies
Cash bonus, percentage of base salary at the discretion of the Compensation Committee of the Board of Directors				30.00%
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus (as a percent)				20.00%
Employment and Consulting Agreements | Kunwar Shailubhai | Minimum
Commitments and contingencies
Enterprise value of the joint venture for receipt of realization bonus				250,000,000
License fees contracted to receive receipt of realization bonus				50,000,000
Enterprise value at the time of the merger or sale for receipt of bonus				400,000,000
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus (as a percent)				20.00%
Enterprise value at the time of merger or sale or twelve months after merger or sale for receipt of bonus				250,000,000
Enterprise value at the time of the merger or sale for receipt of bonus in Scenario 2				1,000,000,000
Beneficial ownership of surviving entity after consummation of the merger, owned by stockholders prior to consummation of the merger or sale for receipt of bonus in scenario 2 (as a percent)				20.00%
Lease agreements | 20th floor of 420 Lexington Avenue, New York
Commitments and contingencies
Extension to existing lease term						3 years
Monthly rate of lease							51,000
Lease agreements | Small laboratory and several offices at Bucks County Biotechnology Center in Doylestown, Pennsylvania
Commitments and contingencies
Monthly rate of lease	$ 3,600