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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
3 Months Ended 100 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Mar. 31, 2014
Cash Flows From Operating Activities:      
Net loss $ (16,225) $ (18,697) $ (187,402)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation 28   94
Distribution of non-cash items 84   84
Loss on disposal of property and equipment     2
Stock-based compensation expense 1,264 1,257 11,362
Accretion of discount/premium on investment securities 24 37 (3)
Purchased in-process research and development     28,157
Change in fair value of derivative instruments-warrants (223) 1,093 (3,993)
Changes in operating assets and liabilities:      
Security deposit     (20)
Accounts payable and accrued expenses (3,011) 700 10,540
Prepaid expenses and other current assets (1,860) (27) (5,578)
Total Adjustments (3,694) 3,060 40,645
Net Cash Used in Operating Activities (19,919) (15,637) (146,757)
Cash Flows From Investing Activities:      
Net cash paid on Exchange Transaction     (155)
Loans to related parties   (270) (3,576)
Sale/(purchases) of available-for-sale securities   8,000 (50,000)
Additions to property and equipment (28) (78) (685)
Repayment on ContraVir loan receivable 455   455
Net Cash (Used in)/Provided by Investing Activities 427 7,652 (53,961)
Cash Flows From Financing Activities:      
Issuance of common stock pursuant to controlled equity sales agreement 22,606 4,671 233,774
Issuance of common stock of ContraVir 3,224   3,224
Fees and expenses-combined (639) (140) (12,985)
Proceeds from exercise of stock warrants     415
Proceeds from exercise of stock options 36 105 155
Distribution associated with ContraVir Spinoff (3,230)   (3,230)
Net Cash Provided by Financing Activities 21,997 4,636 221,353
Net increase/(decrease) in cash and cash equivalents 2,505 (3,349) 20,635
Cash and cash equivalents at beginning of period 18,130 12,416  
Cash and cash equivalents at end of period 20,635 9,067 20,635
Supplementary disclosure of cash flow information:      
Cash paid for taxes 30 18 251
Supplementary disclosure of non-cash investing and financing activities:      
Value of warrants classified as derivative liability-net     5,304
Value of common stock issued to induce stockholders to extend lock-up agreements     3,235
Recapitalization of Synergy   $ 4,904 $ 4,904