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Acquisition and Stockholders' Equity (Deficit) (Details 3) (USD $)
0 Months Ended 3 Months Ended 12 Months Ended 98 Months Ended 0 Months Ended 0 Months Ended 1 Months Ended 3 Months Ended 0 Months Ended 3 Months Ended 12 Months Ended 0 Months Ended 2 Months Ended 0 Months Ended
Jan. 29, 2012
Mar. 31, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Dec. 31, 2013
Jan. 15, 2013
Nov. 20, 2009
Feb. 06, 2014
Subsequent Event
Jan. 28, 2014
ContraVir Subsidiary
Subsequent Event
Dec. 31, 2013
Weighted average
Feb. 06, 2014
Weighted average
Subsequent Event
Oct. 18, 2012
CRO stock purchase agreement
Jan. 31, 2013
CRO stock purchase agreement
Dec. 31, 2012
CRO stock purchase agreement
Mar. 31, 2013
CRO stock purchase agreement
Oct. 17, 2012
CRO stock purchase agreement
Apr. 16, 2013
April 2013 Registered Direct Offering
Dec. 31, 2012
June 21, 2012 Equity sales agreement
Dec. 31, 2013
June 21, 2012 Equity sales agreement
Mar. 14, 2014
June 21, 2012 Equity sales agreement
Subsequent Event
Feb. 27, 2014
June 21, 2012 Equity sales agreement
Subsequent Event
Dec. 31, 2013
June 21, 2012 Equity sales agreement
Weighted average
Jan. 17, 2013
Callisto Merger Agreement
Fair value of common stock issued for services rendered   $ 92,663 $ 250,000 $ 93,000 $ 341,295 $ 18,000 $ 2,000               $ 250,000                      
Common stock issued for services rendered (in shares) 26,272       79,000                         55,000                
Closing stock price (in dollars per share)                                     $ 4.57           $ 6.16  
Percentage of services completed of total contract                                 50.00%                  
Stock based compensation expense     4,614,000 2,515,000 822,000     10,098,000               125,000 125,000                  
Number of authorized shares of common stock     200,000,000 100,000,000       200,000,000 200,000,000 100,000,000                                
Shares approved for distribution                       9,000,000                            
Shares of subsidiary to be distributed for each share of entity's shares outstanding                       0.0986                            
Decrease in exercise price (in dollars per share)                     $ 0.011                              
Warrants outstanding     5,647,203         5,647,203                                    
Exercise price of warrants (in dollars per share)                         $ 5.37 $ 5.359                        
Shares issued in connection with merger                                                   28,605,379
Exchange Ratio of shares                                                   0.1799
Cancellation of stock (in shares)                                                   22,294,976
Lock-up period                                                   24 months
Shares granted in connection with merger                                                   1,221,316
Assets                                                    
Security deposits                                                   74,000
Total assets acquired                                                   74,000
Liabilities                                                    
Accounts payable and other liabilities                                                   (1,400,000)
Net assumed liabilities                                                   (1,326,000)
Elimination of amounts due from Callisto                                                   (3,578,000)
Recapitalization of Synergy     (4,904,000)         (4,904,000)                                   (4,904,000)
Common stock issued (in shares)                                       16,375,000 815,654 758,093 107,808 3,644,143    
Common stock price (in dollars per share)                             $ 4.55         $ 5.50 $ 5.04   $ 6.09 $ 5.82    
Gross proceeds from sale of common stock by the entity     94,734,000 55,862,000 34,369,000     211,168,000                       90,000,000 4,111,802 4,700,000 656,238 21,216,860    
Stock issuance costs     $ 5,623,000 $ 3,774,000 $ 2,148,000     $ 12,346,000                       $ 5,500,000   $ 100,000