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Acquisition and Stockholders' Equity (Deficit) (Details 2) (USD $)
0 Months Ended 3 Months Ended 12 Months Ended 98 Months Ended 12 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended 3 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended 3 Months Ended 0 Months Ended 0 Months Ended 1 Months Ended 0 Months Ended 3 Months Ended 12 Months Ended
Jan. 29, 2012
Mar. 31, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Dec. 31, 2008
Dec. 31, 2013
Dec. 31, 2011
Selling agent
Dec. 31, 2009
Securities purchase agreement 2009
Jul. 08, 2010
June 30, 2010, securities purchase agreements
Jun. 30, 2010
June 30, 2010, securities purchase agreements
Jul. 09, 2010
June 30, 2010, securities purchase agreements
Jul. 31, 2010
June 30, 2010, securities purchase agreements
Aug. 16, 2010
August 16, 2010 securities purchase agreements
Oct. 12, 2010
July 13, 2010 and October 12, 2010 extended lock-up agreement
Jun. 22, 2010
July 13, 2010 and October 12, 2010 extended lock-up agreement
Oct. 01, 2010
October 1, 2010 securities purchase agreements
Oct. 18, 2010
October 18, 2010 securities purchase agreements
Mar. 04, 2011
March 4, 2011 registered direct offering
Dec. 19, 2011
May 2 to May 23, 2011 securities purchase agreements
Oct. 04, 2011
May 2 to May 23, 2011 securities purchase agreements
May 23, 2011
May 2 to May 23, 2011 securities purchase agreements
Jun. 03, 2011
Warrants exercised on June 3, 2011
Dec. 19, 2011
June 3 to June 15, 2011 securities purchase agreements
Jun. 15, 2011
June 3 to June 15, 2011 securities purchase agreements
Jun. 15, 2011
June 3 to June 15, 2011 securities purchase agreements
Dec. 19, 2011
July 11, 2011 securities purchase agreements
Jul. 11, 2011
July 11, 2011 securities purchase agreements
Dec. 07, 2011
July 28, 2011 securities purchase agreements
Jul. 28, 2011
July 28, 2011 securities purchase agreements
Oct. 04, 2011
October 4, 2011 securities purchase agreements
Oct. 19, 2011
October 19, 2011 securities purchase agreements
Oct. 28, 2011
October 28, 2011 securities purchase agreements
Oct. 31, 2011
October 2011 warrants
Nov. 14, 2011
November 14, 2011 securities purchase agreements
Jun. 30, 2013
November 14, 2011 securities purchase agreements
Dec. 01, 2012
November 14, 2011 securities purchase agreements
Selling agent
Dec. 15, 2011
December 2011 Public Offering
Dec. 06, 2011
December 2011 Public Offering
Dec. 07, 2011
December 2011 Public Offering
Dec. 02, 2011
December 2011 Public Offering
Dec. 01, 2011
December 2011 Public Offering
Jun. 06, 2012
May 2012 Public Offering
May 09, 2012
May 2012 Public Offering
Jun. 06, 2012
May 2012 Public Offering
Jun. 21, 2012
June 21, 2012 Equity sales agreement
Dec. 31, 2012
June 21, 2012 Equity sales agreement
Dec. 31, 2013
June 21, 2012 Equity sales agreement
Common stock issued (in shares)                     11,407,213               500,000 305,000 300,000     416,667     193,541     40,458   333,782                                 815,654 758,093
Price per share (in dollars per share)                     $ 1.40                                         $ 7.00                                 $ 5.04  
Warrants issued (in shares)                     0                                         0                                    
Fees and expenses associated with offering     $ 5,623,000 $ 3,774,000 $ 2,148,000 $ 468,000 $ 260,000 $ 73,000   $ 2,148,383 $ 260,002   $ 25,000                                                                       $ 123,385  
Gross proceeds from sale of common stock by the entity     94,734,000 55,862,000 34,369,000       211,168,000   15,970,100                                         2,336,472                           45,000,000 51,750,000   4,111,802 4,700,000
Gross proceeds from offering                       2,499,000 255,000 2,754,000   400,000     2,500,000 1,525,000 1,800,000     2,499,999       1,161,243   242,750     2,348,723 581,876 500,000           15,000,000                  
Number of units issued for services (in units)                   77,750                                                         77,750                      
Number of units sold                         324,000     49,383                                 552,647 136,912 117,647   1,328,941           1,875,000              
Unit price (in dollars per share)                         $ 8.50     $ 8.10     $ 5.00 $ 5.00 $ 6.00     $ 6.00       $ 6.00   $ 6.00     $ 4.25 $ 4.25 $ 4.25           $ 8.00                  
Number of shares of common stock per unit                   1     1     1     1 1                         1 1 1   1           2              
Number of warrants per unit                   1     1     1     0.4 0.4                         1 1 1   1           1              
Number of common shares that can be acquired upon exercise of each warrant                   1     1     1                                 0.5 0.5 0.5   1             1            
Term of warrants                   7 years     5 years     5 years     5 years 5 years 7 years     7 years       7 years   7 years     5 years 5 years 5 years               5 years              
Exercise price of warrants (in dollars per share)                   $ 6.50     $ 9.00     $ 8.50     $ 5.50 $ 5.50 $ 6.20   $ 4.25 $ 4.25     $ 6.50 $ 6.50   $ 6.50     $ 5.50 $ 5.50 $ 5.50               $ 5.50              
Fees paid related to equity offerings     5,623,000 3,774,000 2,148,000       12,346,000           261,630       50,000 91,000                                                 405,000 2,952,930       100,000
Common stock issued as consideration to extend lock-up agreements                                 670,933                                                                  
Percentage of shares of previously issued common stock, which are currently subject to a lock-up agreement                                   5.00%                                                                
Fair value of common stock issued to accomplish lock-up extension                 3,235,000               3,235,040                                                                  
Aggregate number of shares that can be purchased by warrants issued (in shares)                   9,025                 200,000 122,000 210,000     416,667     193,541 193,541   40,458                                        
Period from issuance for which exercise price is protected, in the event of subsequent equity sales at a lower price                                               2 years                                                    
Derivative liabilities reclassified to equity                                           725,000     486,328 315,901     73,931             593,296   3,600,000                        
Exercise of warrant to purchase common stock (in shares)                                                 80,000                                                  
Proceeds from exercise of warrants         415,000       415,000                               415,309                                                  
Purchase price of 49,383 shares (in dollars per share)                                                 $ 5.00                                                  
Number of shares with purchase price of $5.00 per share                                                 49,383                                                  
Purchase price of 30,617 shares (in dollars per share)                                                 $ 5.50                                                  
Number of shares with purchase price of $5.50 per share                                                 30,617                                                  
Maximum period for registration of shares of common stock and shares of common stock underlying the warrants in a resale registration statement                                                       45 days   45 days                                        
Common stock issued to make whole certain shares (in shares)                                                             215,981                                      
Purchase price per share paid including common stock issued to make whole certain shares (in dollars per share)                                                             $ 4.25                                      
Decrease in the prospective exercise proceeds attributable to warrants                                             937,500                                                      
Additional shares of common stock purchased by underwriters to cover over-allotment                                                                                     281,250     1,500,000        
Gross proceeds from exercise of over-allotment option by underwriters                                                                               2,250,000         6,750,000          
Options granted to underwriters and principals (in shares)                                                                                   112,500                
Term of options granted to underwriters and principals                                                                                   3 years                
Exercise price of options granted to underwriters and principals (in dollars per share)                                                                                   $ 5.00                
Warrant term                   5 years                                                                                
Exercise price (in dollars per share)                   $ 5.50                                                                                
Warrants classified to equity instruments (in shares)                   8,025                                                                                
Warrants classified to derivative liability (in shares)                   78,750                                                                                
Common stock issued for services rendered (in shares) 26,272       79,000                                                                                          
Value of common stock issued for professional services rendered, recorded as legal expense   92,663 250,000 93,000 341,295 18,000 2,000                                                                                      
Fair value of common stock issued for services rendered (in dollars per share) $ 3.53                                                                                                  
Number of shares of common stock closed under an underwritten public offering                                                                                           10,000,000        
Common stock price per share for public offering and over-allotment (in dollars per share)                                                                                           $ 4.50        
Period during which underwriters could purchase additional shares to cover over-allotments                                                                                           45 days        
Maximum share amount to be issued and sold under agreement                                                                                               30,000,000    
Attorney's fee                                                                                                 $ 10,000