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Basis of Presentation (Details 2) (USD $)
3 Months Ended 12 Months Ended 98 Months Ended
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2012
Sep. 30, 2012
Jun. 30, 2012
Mar. 31, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2013
Dec. 31, 2010
Basis of Presentation                          
Accumulated deficit $ 171,177,000       $ 109,053,000       $ 171,177,000 $ 109,053,000   $ 171,177,000  
Net cash used in operating activities                 52,631,000 31,125,000 21,231,000 126,838,000  
Cash and cash equivalents 18,130,000       12,416,000       18,130,000 12,416,000 13,245,000 18,130,000 1,707,000
Available-for-sale securities 50,027,000       20,086,000       50,027,000 20,086,000   50,027,000  
Net losses from operations 19,357,000 13,474,000 11,858,000 17,622,000 11,532,000 10,088,000 9,545,000 7,070,000 62,311,000 38,235,000 20,164,000 176,760,000  
Net cash provided by financing activities                 89,230,000 52,088,000 32,636,000 199,356,000  
Working capital $ 56,200,000               $ 56,200,000     $ 56,200,000