CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIT) (USD $)	Total	Common Stock, Par Value	Additional Paid in Capital	Deficit Accumulated during the Development Stage
Balance at Nov. 15, 2005
Increase (Decrease) in Stockholders' Equity
Sale of unregistered common stock to founder	$ 2,000	$ 7,000	$ (5,000)
Sale of unregistered common stock to founder (in shares)		75,690,608
Common stock issued via registered direct offerings, private placements and other	18,000	1,000	17,000
Common stock issued via registered direct offerings, private placements and other (in shares)		6,850,000
Balance at Dec. 31, 2005	20,000	8,000	12,000
Balance (in shares) at Dec. 31, 2005		82,540,608
Increase (Decrease) in Stockholders' Equity
Net loss for the period	(20,000)			(20,000)
Balance at Dec. 31, 2006		8,000	12,000	(20,000)
Balance (in shares) at Dec. 31, 2006		82,540,608
Increase (Decrease) in Stockholders' Equity
Capital contribution by shareholders	9,000		9,000
Net loss for the period	(20,000)			(20,000)
Balance at Dec. 31, 2007	(11,000)	8,000	21,000	(40,000)
Balance (in shares) at Dec. 31, 2007		82,540,608
Increase (Decrease) in Stockholders' Equity
Common stock issued via registered direct offerings, private placements and other	3,025,000		3,025,000
Common stock issued via registered direct offerings, private placements and other (in shares)		2,520,833
Fees and expenses related to financing transactions - paid in cash	(73,000)		(73,000)
Cancellation of unregistered shares		(7,000)	7,000
Cancellation of unregistered shares (in shares)		(74,990,604)
Common stock issued via exchange transactions to former Callisto Shareholders and other	27,280,000	3,000	27,277,000
Common stock issued via exchange transactions to former Callisto Shareholders and other (in shares)		22,732,380
Stock based compensation expense	380,000		380,000
Net loss for the period	(31,757,000)			(31,757,000)
Balance at Dec. 31, 2008	(1,156,000)	4,000	30,637,000	(31,797,000)
Balance (in shares) at Dec. 31, 2008		32,803,217
Increase (Decrease) in Stockholders' Equity
Common stock issued via registered direct offerings, private placements and other	15,970,000	1,000	15,969,000
Common stock issued via registered direct offerings, private placements and other (in shares)		11,407,213
Fees and expenses related to financing transactions - paid in cash	(260,000)		(260,000)
Common stock issued for services rendered	2,000		2,000
Common stock issued for services rendered (in shares)		1,250
Stock based compensation expense	1,052,000		1,052,000
Net loss for the period	(8,124,000)			(8,124,000)
Balance at Dec. 31, 2009	7,484,000	5,000	47,400,000	(39,921,000)
Balance (in shares) at Dec. 31, 2009		44,211,680
Increase (Decrease) in Stockholders' Equity
Fees and expenses related to financing transactions - paid in cash	(468,000)		(468,000)
Common stock issued via registered direct offerings and private placements	7,179,000		7,179,000
Common stock issued via registered direct offerings and private placements (in shares)		1,209,000
Warrants classified to derivative liability - net	(3,785,000)		(3,785,000)
Common stock issued to extend lock-up agreements related to unregistered shares (in shares)		670,933
Common stock issued for services rendered	18,000		18,000
Common stock issued for services rendered (in shares)		2,469
Stock based compensation expense	694,000		694,000
Net loss for the period	(15,221,000)			(15,221,000)
Balance at Dec. 31, 2010	(4,099,000)	5,000	51,038,000	(55,142,000)
Balance (in shares) at Dec. 31, 2010		46,094,082
Increase (Decrease) in Stockholders' Equity
Fees and expenses related to financing transactions - paid in cash	(2,148,000)		(2,148,000)
Common stock issued via registered direct offerings and private placements	34,369,000	1,000	34,368,000
Common stock issued via registered direct offerings and private placements (in shares)		7,733,093
Fees and expenses related to financing transactions - paid in units of common stock and warrants (in shares)		77,750
Warrants classified to derivative liability - net	(5,094,000)		(5,094,000)
Common stock issued to make whole certain unregistered shares (in shares)		215,981
Exercise of warrant	415,000		415,000
Exercise of warrant (in shares)		80,000
Common stock issued for services rendered	341,000		341,000
Common stock issued for services rendered (in shares)		79,000
Stock based compensation expense	481,000		481,000
Net loss for the period	(14,467,000)			(14,467,000)
Balance at Dec. 31, 2011	9,798,000	6,000	79,401,000	(69,609,000)
Balance (in shares) at Dec. 31, 2011		54,279,906
Increase (Decrease) in Stockholders' Equity
Common stock issued via registered direct offerings, private placements and other	55,862,000	1,000	55,861,000
Common stock issued via registered direct offerings, private placements and other (in shares)		12,315,654
Fees and expenses related to financing transactions - paid in cash	(3,774,000)		(3,774,000)
Common stock issued for services rendered	93,000		93,000
Common stock issued for services rendered (in shares)		26,272
Stock based compensation expense	2,297,000		2,297,000
Net loss for the period	(39,444,000)			(39,444,000)
Balance at Dec. 31, 2012	24,832,000	7,000	133,878,000	(109,053,000)
Balance (in shares) at Dec. 31, 2012	66,621,832	66,621,832
Increase (Decrease) in Stockholders' Equity
Common stock issued via registered direct offerings, private placements and other	94,734,000	2,000	94,732,000
Common stock issued via registered direct offerings, private placements and other (in shares)		17,133,093
Fees and expenses related to financing transactions - paid in cash	(5,623,000)		(5,623,000)
Cancellation of unregistered shares		(2,000)	2,000
Cancellation of unregistered shares (in shares)		(22,294,976)
Common stock issued via exchange transactions to former Callisto Shareholders and other		3,000	(3,000)
Common stock issued via exchange transactions to former Callisto Shareholders and other (in shares)		28,605,379
Fair value of warrants reclassified to additional paid in capital	3,575,000		3,575,000
Recapitalization of Synergy	(4,904,000)		(4,904,000)
Common stock issued for services rendered	250,000		250,000
Common stock issued for services rendered (in shares)		55,000
Exercise of stock options	119,000		119,000
Exercise of stock options (in shares)		61,787
Stock based compensation expense	3,133,000		3,133,000
Net loss for the period	(42,273,000)			(42,273,000)
Balance at Sep. 30, 2013	$ 73,843,000	$ 10,000	$ 225,159,000	$ (151,326,000)
Balance (in shares) at Sep. 30, 2013	90,182,115	90,182,115