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Income Taxes (Details 2) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 12 Months Ended 36 Months Ended 86 Months Ended
Dec. 31, 2012
Jun. 30, 2012
Dec. 31, 2011
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2012
Dec. 31, 2012
Income taxes                
Tax credit awards reported as other income $ 250 $ 256 $ 362 $ 506 $ 362 $ 494 $ 1,362 $ 1,363
Federal | Qualifying Therapeutic Discovery Project
               
Income taxes                
Tax credit awards reported as other income           244   244
New York | Biotechnology Tax Credit
               
Income taxes                
Tax credit awards reported as other income       250 116 250   616
New York | QETC credit
               
Income taxes                
Tax credit awards reported as other income       $ 256 $ 246     $ 502