<SEC-DOCUMENT>0001047469-17-000496-index.html : 20170202
<SEC-HEADER>0001047469-17-000496.hdr.sgml : 20170202
<ACCEPTANCE-DATETIME>20170202163017
ACCESSION NUMBER:		0001047469-17-000496
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20170202
DATE AS OF CHANGE:		20170202

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SYNERGY PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001347613
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				330505269
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-205484
		FILM NUMBER:		17568654

	BUSINESS ADDRESS:	
		STREET 1:		420 LEXINGTON AVENUE
		STREET 2:		SUITE 2012
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10170
		BUSINESS PHONE:		212-297-0010

	MAIL ADDRESS:	
		STREET 1:		420 LEXINGTON AVENUE
		STREET 2:		SUITE 2012
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10170

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Synergy Pharmaceuticals, Inc.
		DATE OF NAME CHANGE:	20080812

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PAWFECT FOODS INC
		DATE OF NAME CHANGE:	20051221
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>a2230823z424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: a2230823z424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g697110.jpg
<DESCRIPTION>G697110.JPG
<TEXT>
Document 2 - file: g697110.jpg

</DOCUMENT>
</SEC-DOCUMENT>