X0202 3 2006-01-31 0 0001002637 MILLENNIUM PHARMACEUTICALS INC MLNM 0001347582 Protopapas Anna MILLENNIUM PHARMACEUTICALS, INC. 40 LANDSDOWNE STREET CAMBRIDGE MA 02139 0 1 0 0 Senior Vice President Employee stock option (right to buy) 8.38 2015-05-31 Common stock 8333 D Became exercisable for 2/48ths of the total number of shares granted on 05/31/2005 and for 1/48th of the total number of shares granted monthly thereafter beginning 06/01/2005. This is the second of two Forms 3 filed by the reporting person on the same date. This continues the information provided in Table II of the first Form 3 filed on this date. Jean L. Ernst, Attorney-In-Fact 2006-02-08