144 0001806596 XXXXXXXX LIVE 0001347178 Vanda Pharmaceuticals Inc. 001-34186 2200 PENNSYLVANIA AVE NW SUITE 300E WASHINGTON CA 20037 202-734-3400 Moran Kevin Patrick Officer Common Stock Merrill Lynch

1152 15th St., NW Suite 6000 Washington DC 20005

16000 106667.00 57444139 06/15/2023 NASDAQ Common Stock 01/01/2017 Vesting/Settlement of Restricted Stock Units Issuer N 2500 01/01/2017 Compensation Common Stock 03/01/2018 Vesting/Settlement of Restricted Stock Units Issuer N 1287 03/01/2018 Compensation Common Stock 01/01/2019 Vesting/Settlement of Restricted Stock Units Issuer N 1834 01/01/2019 Compensation Common Stock 02/28/2019 Vesting/Settlement of Restricted Stock Units Issuer N 5419 02/28/2019 Compensation Common Stock 03/01/2019 Vesting/Settlement of Restricted Stock Units Issuer N 398 03/01/2019 Compensation Common Stock 01/01/2020 Vesting/Settlement of Restricted Stock Units Issuer N 1503 01/01/2020 Compensation Common Stock 03/01/2020 Vesting/Settlement of Restricted Stock Units Issuer N 1296 03/01/2020 Compensation Common Stock 02/28/2021 Vesting/Settlement of Restricted Stock Units Issuer N 1763 02/28/2021 Compensation Y 06/15/2023 /s/ Kevin Patrick Moran