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Stock-Based Compensation - Summary of Assumptions Used in Black-Scholes Option Pricing Model (Detail)
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Risk-free interest rate, minimum 2.85% 1.85% 2.51% 1.85%
Risk-free interest rate, maximum 2.94% 1.88% 2.94% 2.57%
Expected volatility, minimum 85.70%   85.70% 75.30%
Expected volatility   83.30%    
Expected volatility, maximum 92.80%   92.80% 83.30%
Expected dividend yield 0.00% 0.00% 0.00% 0.00%
Employee Options [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected life of options (in years) 6 years 3 months 6 years 3 months 6 years 3 months 6 years 3 months
Nonemployee Options [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Expected life of options (in years)   10 years   10 years