Commitments and Contingencies - Additional Information (Detail) $ in Thousands		1 Months Ended		3 Months Ended
	Mar. 06, 2025 lawsuit	Jul. 31, 2021	Jul. 31, 2019 agreement	Mar. 31, 2025 USD ($)	Mar. 19, 2025 item	Mar. 31, 2024 USD ($)	Dec. 31, 2024 USD ($)
Other Commitments [Line Items]
Number of lawsuits filed | lawsuit	2
Number of demands received | item					13
Number of draft complaints received | item					3
Operating lease right-of-use assets				$ 0			$ 0
Operating lease liabilities				0			$ 0
Terminated Corporate Headquarters
Other Commitments [Line Items]
Operating Lease, expense						$ 269
Terminated Corporate Headquarters | Research and Development [Member]
Other Commitments [Line Items]
Operating Lease, expense						173
Terminated Corporate Headquarters | General and Administrative [Member]
Other Commitments [Line Items]
Operating Lease, expense						96
Non-Exclusive License Agreement [Member] | Enteris Biopharma, Inc. [Member]
Other Commitments [Line Items]
Payment of milestone payment				$ 0		$ 0
MSA [Member] | Patheon and Patheon Manufacturing Services LLC [Member]
Other Commitments [Line Items]
Number of related product agreements | agreement			2
MSA [Member] | Patheon [Member]
Other Commitments [Line Items]
Agreement renewal term			2 years
Agreement initial term, expiration date			Dec. 31, 2024
Agreement expiration date			Dec. 31, 2026
API Commercial Supply Agreement - PPL [Member]
Other Commitments [Line Items]
Agreement renewal term		5 years