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Stock-Based Compensation (Tables)
3 Months Ended
Mar. 31, 2025
Summary of Assumptions Used in Black-Scholes Option Pricing Model

Three Months Ended

March 31, 

    

2025

    

2024

    

Risk-free interest rate

 

4.12%

 

Expected volatility

 

89.6%

 

Expected dividend yield

 

0%

 

Expected life of employee and Board options (in years)

 

6.25

 

Summary of Stock Option Activity

Weighted

Number of

Average Exercise

    

Shares

    

 Price

    

Outstanding, December 31, 2024

 

113,487

$

319.80

 

Granted

 

 

 

Exercised

 

 

 

Forfeited

 

 

 

Expired

 

 

 

Outstanding, March 31, 2025

 

113,487

$

319.80

Options exercisable, March 31, 2025

 

64,989

Employees And Non-Employee Members Of Board Of Directors  
Summary of Restricted Stock Unit Activity

Weighted

Number of

Average Grant

    

Units

    

Date Fair Value

Outstanding, December 31, 2024

 

26,638

$

52.53

Awarded

 

 

Vested and released

 

(792)

 

447.95

Forfeited

 

 

Outstanding, March 31, 2025

 

25,846

$

40.39

Restricted stock units exercisable (vested and deferred), March 31, 2025

 

Employee Stock Option  
Summary of Compensation Expense Recognized

Three Months Ended

March 31, 

    

2025

    

2024

    

Research and development

$

$

504

General and administrative

 

1,100

 

1,229

Total stock option expense

$

1,100

$

1,733

Restricted Stock Units  
Summary of Compensation Expense Recognized

Three Months Ended

March 31, 

    

2025

2024

Research and development

 

$

$

255

General and administrative

326

1,357

Total restricted stock unit expense

 

$

326

$

1,612