Accounts Payable and Accrued Expenses - Schedule of Accounts Payable and Accrued Expenses (Detail) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Accounts Payable and Accrued Expenses
Accounts payable	$ 1,434	$ 11,583
Accrued research projects	64	4,343
Accrued compensation and benefits	565	6,519
Accrued professional fees and other	1,909	3,147
Total	$ 3,972	$ 25,592