CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Common Stock	Additional Paid-In Capital	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)	Total
Balance, Value at Dec. 31, 2021	$ 4	$ 708,634	$ (480,758)	$ (358)	$ 227,522
Balance, Shares at Dec. 31, 2021	4,456,734
Stock-based compensation expense		14,345			14,345
Shares issued upon exercise of stock options, value		311			311
Shares issued upon exercise of stock options, shares	4,026
Shares issued upon vesting of restricted stock units, value		3,389			3,389
Shares issued upon vesting of restricted stock units, shares	22,352
Net loss			(85,474)		(85,474)
Other comprehensive income (loss)				(1,314)	(1,314)
Balance, Value at Dec. 31, 2022	$ 4	726,679	(566,232)	(1,672)	158,779
Balance, Shares at Dec. 31, 2022	4,483,112
Net proceeds from sales of common stock under open market sales agreement		1,117			1,117
Net proceeds from sales of common stock under open market sales agreement (shares)	32,240
Stock-based compensation expense		12,710			12,710
Shares issued upon exercise of stock options, value	$ 1	559			560
Shares issued upon exercise of stock options, shares	7,768
Shares issued upon vesting of restricted stock units, value		1,020			1,020
Shares issued upon vesting of restricted stock units, shares	16,939
Net loss			(118,513)		(118,513)
Other comprehensive income (loss)				1,412	1,412
Balance, Value at Dec. 31, 2023	$ 5	742,085	(684,745)	(260)	57,085
Balance, Shares at Dec. 31, 2023	4,540,059
Stock-based compensation expense		6,709			6,709
Shares issued upon vesting of restricted stock units, value		2,220			2,220
Shares issued upon vesting of restricted stock units, shares	31,170
Net loss			(70,867)		(70,867)
Other comprehensive income (loss)				$ 260	260
Balance, Value at Dec. 31, 2024	$ 5	$ 751,014	$ (755,612)		$ (4,593)
Balance, Shares at Dec. 31, 2024	4,571,229