Commitments and Contingencies - Additional Information (Detail) $ in Thousands					1 Months Ended		3 Months Ended		9 Months Ended
	Nov. 01, 2024 USD ($)	Sep. 26, 2024 USD ($)	Jul. 28, 2023 USD ($)	May 11, 2023 USD ($)	Jul. 31, 2021	Jul. 31, 2019 agreement	Sep. 30, 2024 USD ($)	Sep. 30, 2023 USD ($)	Sep. 30, 2024 USD ($)	Sep. 30, 2023 USD ($)	Sep. 25, 2024 USD ($)	Dec. 31, 2023 USD ($)
Other Commitments [Line Items]
Accounts payable and accrued expenses							$ 6,622		$ 6,622			$ 25,592
Operating lease right-of-use assets												4,864
Operating lease liability - current							3,417		3,417
Cash payment relating to operating leases							4,363	$ 500	4,363	$ 1,489
New Corporate Headquarters Office Space [Member]
Other Commitments [Line Items]
Lease, annual fixed rent				$ 1,300
Lease, fixed rent, annual increase, percent				2.50%
Option to extend				true
Operating Lease, renewable term				5 years
Discount rate - operating leases				12.83%
Operating lease liabilities			$ 6,672
Lessee, operating lease, incentives			2,900
Operating lease right-of-use assets			$ 6,779
Lease incentives reimbursed									2,094
Lease incentives remaining to be reimbursed									0
Operating Lease, expense							241	214	766	214
New Corporate Headquarters Office Space [Member] | Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member]
Other Commitments [Line Items]
Lessee, operating lease, discount rate, basis spread on variable rate				7.75%
Lessee, operating lease, discount rate, variable rate basis, floor				2.75%
New Corporate Headquarters Office Space [Member] | Research and Development [Member]
Other Commitments [Line Items]
Operating Lease, expense								150	368	150
New Corporate Headquarters Office Space [Member] | General and Administrative [Member]
Other Commitments [Line Items]
Operating Lease, expense							241	64	398	64
Assignment of New Lease
Other Commitments [Line Items]
Operating lease, cash lease payments		$ 3,238
Operating lease, release payments		1,125
Operating lease, initial direct costs capitalized		577
Operating lease liability - current		3,417									$ 7,780
Cash payment relating to operating leases		$ 4,363
Impairment charge in ROU asset							4,274		4,274
Non-cash lease payments							3,417		3,417
Assignment of New Lease | Subsequent Event [Member]
Other Commitments [Line Items]
Operating lease, non-cash lease payments	$ 3,417
Patheon and Patheon Manufacturing Services LLC [Member]
Other Commitments [Line Items]
Reduced demand payment for manufacturing commitments												$ 1,700
Old Stamford Operating Lease [Member]
Other Commitments [Line Items]
Operating lease cost							0	407	0	1,220
Old Stamford Operating Lease [Member] | Research and Development [Member]
Other Commitments [Line Items]
Operating lease cost								285		854
Old Stamford Operating Lease [Member] | General and Administrative [Member]
Other Commitments [Line Items]
Operating lease cost								122		366
New Stamford Lease [Member]
Other Commitments [Line Items]
Letter of credit amount outstanding							1,500		1,500
Non-Exclusive License Agreement [Member] | Enteris Biopharma, Inc. [Member]
Other Commitments [Line Items]
Payment of milestone payment							$ 0	$ 0	$ 0	$ 0
MSA [Member] | Patheon and Patheon Manufacturing Services LLC [Member]
Other Commitments [Line Items]
Number of related product agreements | agreement						2
API Commercial Supply Agreement - PPL [Member]
Other Commitments [Line Items]
Agreement renewal term					5 years
Agreement successive renewal term									2 years