CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023
Operating activities
Net loss	$ (63,188)	$ (86,176)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense	6,575	10,129
Non-cash interest expense on liability related to sales of future royalties and milestones, net of issuance costs accretion	5,852
Impairment of long-lived assets	4,274
Inventory write-down	2,509
Depreciation and amortization	192	177
Noncash lease expense	766	1,221
Accretion of available-for-sale marketable securities, net	(543)	(159)
Changes in operating assets and liabilities:
Accounts receivable, net - related party	2,330	(91)
Inventory	(313)	(883)
Income tax receivable	697
Other receivables	(379)	(1,186)
Prepaid expenses	5,772	3,609
Accounts payable and accrued expenses	(19,149)	37
Operating lease liability	(4,363)	(1,278)
Reimbursement of lease incentive	2,094
Other		(108)
Net cash used in operating activities	(56,874)	(74,708)
Investing activities
Proceeds from maturities of available-for-sale marketable securities	77,000	118,590
Proceeds from redemptions of available-for-sale marketable securities, at par		4,000
Purchases of available-for-sale marketable securities	(32,213)	(48,601)
Purchases of property and equipment	(1,046)	(323)
Net cash provided by investing activities	43,741	73,666
Financing activities
Payments to royalty purchase and sale agreement	(1,989)
Net proceeds from sales of common stock under open market sales agreement		1,117
Proceeds from the exercise of stock options		559
Net cash (used in) provided by financing activities	(1,989)	1,676
Net (decrease) increase in cash, cash equivalents and restricted cash	(15,122)	634
Cash, cash equivalents and restricted cash at beginning of period	53,683	64,149
Cash, cash equivalents and restricted cash at end of period	38,561	64,783
Noncash investing and financing activities
Incremental right-of-use asset in exchange for non-cash lease liability from modification of lease	3,417
Initial direct costs included as right-of-use asset from modification of lease	$ 577
Accrual for leasehold improvements		$ 807