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CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Revenue:    
Total revenue $ 2,135 $ 6,165
Operating expenses:    
Cost of goods sold 620 2,590
Research and development 21,964 24,334
General and administrative 6,816 6,891
Restructuring 2,401  
Total operating expenses 31,801 33,815
Operating loss (29,666) (27,650)
Other income, net 952 985
Non-cash interest expense on liability related to sales of future royalties and milestones (1,982)  
Net loss $ (30,696) $ (26,665)
Net loss per share:    
Basic $ (0.56) $ (0.49)
Diluted $ (0.56) $ (0.49)
Weighted average shares:    
Basic 54,588,090 53,872,038
Diluted 54,588,090 53,872,038
Other comprehensive income, net of tax of $0:    
Change in unrealized gains on available-for-sale marketable securities $ 69 $ 571
Total comprehensive loss (30,627) (26,094)
Collaborative revenue    
Revenue:    
Total revenue 788 2,750
Commercial supply revenue    
Revenue:    
Total revenue 640 3,191
Royalty revenue    
Revenue:    
Total revenue   125
Clinical compound revenue    
Revenue:    
Total revenue 84 $ 99
Other revenue    
Revenue:    
Total revenue $ 623