Commitments and Contingencies - Additional Information (Detail) $ in Thousands			1 Months Ended		3 Months Ended		9 Months Ended
	Jul. 28, 2023 USD ($)	May 11, 2023 USD ($)	Jul. 31, 2021	Jul. 31, 2019 agreement	Sep. 30, 2023 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2023 USD ($)	Sep. 30, 2022 USD ($)	Dec. 31, 2022 USD ($)
Other Commitments [Line Items]
Operating lease liabilities					$ 7,312		$ 7,312
Operating lease right-of-use assets					7,108		7,108		$ 1,551
New Corporate Headquarters Office Space [Member]
Other Commitments [Line Items]
Lease, annual fixed rent		$ 1,300
Lease, fixed rent, annual increase, percent		2.50%
Option to extend		true
Operating Lease, renewable term		5 years
Operating lease liabilities	$ 6,672
Discount rate - operating leases		12.83%
Lessee, operating lease, incentives	2,900
Operating lease right-of-use assets	$ 6,779
Operating Lease, expense					214		214
New Corporate Headquarters Office Space [Member] | Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member]
Other Commitments [Line Items]
Lessee, operating lease, discount rate, basis spread on variable rate		7.75%
Lessee, operating lease, discount rate, variable rate basis, floor		2.75%
New Corporate Headquarters Office Space [Member] | Research and Development [Member]
Other Commitments [Line Items]
Operating Lease, expense					150		150
New Corporate Headquarters Office Space [Member] | General and Administrative [Member]
Other Commitments [Line Items]
Operating Lease, expense					64		64
Stamford Operating Lease [Member]
Other Commitments [Line Items]
Operating lease cost					407	$ 406	1,220	$ 1,218
Stamford Operating Lease [Member] | Research and Development [Member]
Other Commitments [Line Items]
Operating lease cost					285	284	854	853
Stamford Operating Lease [Member] | General and Administrative [Member]
Other Commitments [Line Items]
Operating lease cost					122	122	366	365
Non-Exclusive License Agreement | Enteris Biopharma, Inc. [Member]
Other Commitments [Line Items]
Payment of milestone payment					$ 0	$ 5,000	$ 0	$ 5,000
Patheon MSA [Member] | Patheon and Patheon Manufacturing Services LLC [Member]
Other Commitments [Line Items]
Number of related product agreements | agreement				2
API Commercial Supply Agreement - PPL [Member]
Other Commitments [Line Items]
Agreement renewal term			5 years