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CONDENSED STATEMENTS OF COMPREHENSIVE LOSS - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Revenue:        
Total revenue $ 4,866 $ 10,813 $ 17,964 $ 38,606
Operating expenses:        
Cost of goods sold 1,558 3,055 5,566 5,136
Research and development 25,451 24,691 80,095 65,869
General and administrative 6,755 6,912 21,191 23,829
Total operating expenses 33,764 34,658 106,852 94,834
Operating loss (28,898) (23,845) (88,888) (56,228)
Other income, net 866 665 2,712 1,093
Net loss $ (28,032) $ (23,180) $ (86,176) $ (55,135)
Net loss per share:        
Basic $ (0.52) $ (0.43) $ (1.59) $ (1.03)
Diluted $ (0.52) $ (0.43) $ (1.59) $ (1.03)
Weighted average shares:        
Basic 54,235,695 53,726,123 54,038,239 53,616,753
Diluted 54,235,695 53,726,123 54,038,239 53,616,753
Other comprehensive income (loss), net of tax of $0:        
Change in unrealized gains (losses) on available-for-sale marketable securities $ 291 $ (101) $ 1,233 $ (1,790)
Total comprehensive loss (27,741) (23,281) (84,943) (56,925)
Collaborative revenue        
Revenue:        
Total revenue 2,471 7,443 10,631 15,446
Commercial supply revenue        
Revenue:        
Total revenue 1,252 $ 3,370 5,843 8,160
Royalty revenue        
Revenue:        
Total revenue 167   415  
License and milestone fees        
Revenue:        
Total revenue 910   910 $ 15,000
Clinical compound revenue        
Revenue:        
Total revenue $ 66   $ 165