Income Taxes - Schedule of Significant Components of Company's Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Income Taxes
Valuation allowance	$ (160,814)	$ (143,388)
Deferred tax assets:
Net operating loss carryforwards	113,058	113,636
Federal and state tax credits	26,358	24,428
Stock-based compensation expense	3,434	5,023
Intangible asset amortization	17,265
Other	1,167	1,268
Deferred tax assets	161,282	144,355
Deferred tax liabilities:
Other	(468)	(967)
Deferred tax liabilities	$ (468)	$ (967)