Aggregate offering price of securities.

No definition available.

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- Definition

The number of votes that each common stock receives.

+ References

No definition available.

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- Definition

The percentage of gross proceeds on sales of stock that makes up the commission.

+ References

No definition available.

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- Definition

The amount of upfront fee payable.

+ References

No definition available.

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- Definition

Face amount or stated value per share of common stock.

+ References

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- Definition

The maximum number of common shares permitted to be issued by an entity's charter and bylaws.

+ References

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- Definition

Total number of common shares of an entity that have been sold or granted to shareholders (includes common shares that were issued, repurchased and remain in the treasury). These shares represent capital invested by the firm's shareholders and owners, and may be all or only a portion of the number of shares authorized. Shares issued include shares outstanding and shares held in the treasury.

+ References

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- Definition

Number of shares of common stock outstanding. Common stock represent the ownership interest in a corporation.

+ References

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-Name Accounting Standards Codification
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- Definition

Face amount or stated value per share of preferred stock nonredeemable or redeemable solely at the option of the issuer.

+ References

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- Definition

The maximum number of nonredeemable preferred shares (or preferred stock redeemable solely at the option of the issuer) permitted to be issued by an entity's charter and bylaws.

+ References

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- Definition

Total number of nonredeemable preferred shares (or preferred stock redeemable solely at the option of the issuer) issued to shareholders (includes related preferred shares that were issued, repurchased, and remain in the treasury). May be all or portion of the number of preferred shares authorized. Excludes preferred shares that are classified as debt.

+ References

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- Definition

Aggregate share number for all nonredeemable preferred stock (or preferred stock redeemable solely at the option of the issuer) held by stockholders. Does not include preferred shares that have been repurchased.

+ References

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- Definition

Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

+ References

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (a)(1)
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- Definition

The number of equity-based payment instruments, excluding stock (or unit) options, that vested during the reporting period.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
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-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(2)(iii)(02)
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- Definition

Number of new stock issued during the period.

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- Definition

Total number of shares issued during the period, including shares forfeited, as a result of Restricted Stock Awards.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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Stockholders' Equity - Additional Information (Detail) $ / shares in Units, $ in Thousands		1 Months Ended														2 Months Ended	3 Months Ended	12 Months Ended
	Jun. 04, 2020	Dec. 31, 2022 $ / shares shares	Oct. 31, 2022 shares	Sep. 30, 2022 shares	Jun. 30, 2022 shares	Mar. 31, 2022 USD ($) shares	Feb. 28, 2022 shares	Oct. 31, 2021 shares	Aug. 31, 2021 shares	Jun. 30, 2021 shares	Feb. 28, 2021 shares	Dec. 31, 2020 shares	Oct. 31, 2020 shares	Jun. 30, 2020 shares	Feb. 29, 2020	Mar. 31, 2021 shares	Jun. 30, 2020 shares	Dec. 31, 2022 item $ / shares shares	Dec. 31, 2021 $ / shares shares	Dec. 31, 2020 shares	Aug. 31, 2019 USD ($)
Sale Of Stock [Line Items]
Common stock, shares authorized		100,000,000																100,000,000	100,000,000
Common stock, shares issued		53,797,341																53,797,341	53,480,812
Common stock, shares outstanding		53,797,341																53,797,341	53,480,812
Common stock, par value \| $ / shares		$ 0.001																$ 0.001	$ 0.001
Preferred stock, shares authorized		5,000,000																5,000,000	5,000,000
Preferred stock, par value \| $ / shares		$ 0.001																$ 0.001	$ 0.001
Preferred stock, shares issued		0																0	0
Preferred stock, shares outstanding		0																0	0
Number of votes for each share of common stock \| item																		1
Regulatory Milestones [Member] \| Vifor International Ltd. [Member]
Sale Of Stock [Line Items]
Common stock, shares issued								3,282,391
Non-Exclusive License Agreement \| Enteris Biopharma, Inc. [Member]
Sale Of Stock [Line Items]
Upfront fee \| $																					$ 8,000
Exclusive License Agreement [Member] \| Vifor International Ltd. [Member]
Sale Of Stock [Line Items]
Common stock, shares issued													2,939,552
Unsold Securities Under Shelf Registration Statement dated April 4, 2019 [Member]
Sale Of Stock [Line Items]
Aggregate offering price of securities \| $						$ 154,525
Open Market Sales Agreement [Member] \| Jeffries LLC [Member]
Sale Of Stock [Line Items]
Common stock, shares issued																		0
Stock Sale Commission Percentage						3.00%
Open Market Sales Agreement [Member] \| Maximum [Member] \| Jeffries LLC [Member]
Sale Of Stock [Line Items]
Aggregate offering price of securities \| $						$ 80,000
2022 Shelf Registration Statement [Member] \| Maximum [Member]
Sale Of Stock [Line Items]
Aggregate offering price of securities \| $						$ 300,000
Common Stock
Sale Of Stock [Line Items]
Restricted stock units vested shares																		268,222	189,421	156,584
Restricted Stock Units [Member] \| 2014 Equity Incentive Plan [Member] \| Director [Member] \| June 2020 [Member]
Sale Of Stock [Line Items]
Vesting period of awards granted	1 year
Restricted stock units, vested										36,000
Restricted Stock Units [Member] \| Chief Executive Officer \| 2014 Equity Incentive Plan [Member] \| Director [Member] \| June 2020 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested										36,000
Restricted Stock Units [Member] \| Common Stock \| Board of Directors Chairman [Member] \| June 2022 [Member]
Sale Of Stock [Line Items]
Restricted stock units vested shares					11,876
Restricted Stock Units [Member] \| Common Stock \| Director [Member] \| June 2022 [Member]
Sale Of Stock [Line Items]
Vesting period of awards granted					1 year
Restricted stock units, vested					43,200
Restricted Stock Units [Member] \| Common Stock \| Director [Member] \| June 2021 [Member]
Sale Of Stock [Line Items]
Vesting period of awards granted										1 year
Restricted stock units vested shares										36,000
Restricted Stock Units [Member] \| Common Stock \| Director [Member] \| June 2020 [Member]
Sale Of Stock [Line Items]
Vesting period of awards granted														1 year
Restricted stock units, vested														24,000
Restricted Stock Units [Member] \| Common Stock \| Former Chief Executive Officer [Member] \| June 2022 [Member]
Sale Of Stock [Line Items]
Restricted stock units vested shares					33,999
Performance Restricted Stock Units [Member] \| 2014 Equity Incentive Plan [Member] \| Executive Officers [Member] \| December 2020 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested												36,750
Performance Restricted Stock Units [Member] \| Common Stock \| Executive Officers [Member] \| December 2022
Sale Of Stock [Line Items]
Restricted stock units, vested		26,204
Performance Restricted Stock Units [Member] \| Common Stock \| Executive Officers [Member] \| March 2022 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested						37,999
Performance Restricted Stock Units [Member] \| Common Stock \| Executive Officers [Member] \| August 2021 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested									44,002
Performance Restricted Stock Units [Member] \| Common Stock \| Executive Officers [Member] \| February and March 2021 [Member]
Sale Of Stock [Line Items]
Restricted stock units vested shares																76,750
Performance Restricted Stock Units [Member] \| Common Stock \| Executive Officers [Member] \| April And June 2020 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested																	95,834
Time-based Restricted Stock Units [Member] \| 2014 Equity Incentive Plan [Member] \| Executive Officers [Member] \| February 2020 [Member]
Sale Of Stock [Line Items]
Vesting period of awards granted															3 years
Restricted stock units, vested					16,666		32,666				32,669							82,001
Time-based Restricted Stock Units [Member] \| 2014 Equity Incentive Plan [Member] \| Executive Officers [Member] \| October 2022 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested																		0
Time-based Restricted Stock Units [Member] \| 2014 Equity Incentive Plan [Member] \| Interim Principal Financial and Accounting Officer [Member] \| June 2022 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested																		7,500
Time-based Restricted Stock Units [Member] \| 2014 Equity Incentive Plan [Member] \| Chief Executive Officer [Member] \| October 2021 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested			35,500															41,442
Time-based Restricted Stock Units [Member] \| 2014 Equity Incentive Plan [Member] \| Chief Executive Officer [Member] \| October 2022 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested			35,500
Time-based Restricted Stock Units [Member] \| Common Stock \| Executive Officers [Member] \| March 2022 [Member]
Sale Of Stock [Line Items]
Vesting period of awards granted						3 years
Restricted stock units vested shares						39,278
Time-based Restricted Stock Units [Member] \| Common Stock \| Executive Officers [Member] \| February 2022 [Member]
Sale Of Stock [Line Items]
Vesting period of awards granted							3 years
Restricted stock units vested shares							32,666
Time-based Restricted Stock Units [Member] \| Common Stock \| Executive Officers [Member] \| February 2021 [Member]
Sale Of Stock [Line Items]
Vesting period of awards granted											3 years
Restricted stock units vested shares											32,669
Time-based Restricted Stock Units [Member] \| Common Stock \| Interim Principal Financial and Accounting Officer [Member] \| September 2022 [Member]
Sale Of Stock [Line Items]
Restricted stock units, vested				7,500