Accounts Payable and Accrued Expenses - Schedule of Accounts Payable and Accrued Expenses (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Accounts Payable and Accrued Expenses
Accounts payable	$ 9,604	$ 5,625
Accrued research projects	5,200	4,648
Accrued compensation and benefits	5,219	4,959
Accrued professional fees and other	1,517	629
Total	$ 21,540	$ 15,861