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Summary of Significant Accounting Policies - Concentration of Credit Risk (Detail)
12 Months Ended
Dec. 31, 2022
Institution
item
Dec. 31, 2021
Dec. 31, 2020
Concentration Risk [Line Items]      
Number of suppliers | item 3    
Maximum [Member]      
Concentration Risk [Line Items]      
Period that would require for locating and qualifying alternate sources if the suppliers fail to meet supply commitments 2 years    
Revenue from Contract with Customer Benchmark [Member] | Customer Concentration Risk [Member] | CSL Vifor [Member]      
Concentration Risk [Line Items]      
Concentration of revenue percentage 100.00% 92.00% 100.00%
Cash And Cash Equivalents And Marketable Securities [Member]      
Concentration Risk [Line Items]      
Number Of Financial Institutions | Institution 3