Summary of Significant Accounting Policies - Additional Information (Detail) $ in Thousands	12 Months Ended
	Dec. 31, 2022 USD ($) item segment	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Summary Of Significant Accounting Policies [Line Items]
Prepaid R&D expense | $	$ 15,188	$ 1,481
Expected dividend yield	0.00%	0.00%	0.00%
Number of operating segments | segment	1
Commercial Supply Revenue
Summary Of Significant Accounting Policies [Line Items]
Number of parties in net profit sharing arrangement | item	2
CSL Vifor and CKDP Agreements [Member] | License and Milestone Fees
Summary Of Significant Accounting Policies [Line Items]
Number of performance obligations for revenue recognized | item	1
Prior to Regulatory Approval [Member]
Summary Of Significant Accounting Policies [Line Items]
Cost of goods sold | $		$ 0	$ 0
Options [Member]
Summary Of Significant Accounting Policies [Line Items]
Expected life of options (in years)	6 years 3 months	6 years 3 months	6 years 3 months
Expected dividend yield	0.00%	0.00%	0.00%