Commitments and Contingencies - Additional Information (Detail) $ in Thousands		1 Months Ended		3 Months Ended		9 Months Ended
	Aug. 20, 2019 USD ($)	Jul. 31, 2021	Jul. 31, 2019 agreement	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)
Enteris Biopharma, Inc. [Member]
Other Commitments [Line Items]
Milestone payment earned by 3rd party				$ 5,000			$ 10,000
Stamford Operating Lease and New Stamford Lease [Member]
Other Commitments [Line Items]
Operating lease cost				406	$ 406	$ 1,218	1,218
Stamford Operating Lease and New Stamford Lease [Member] | Research and Development [Member]
Other Commitments [Line Items]
Operating lease cost				284	284	853	853
Stamford Operating Lease and New Stamford Lease [Member] | General and Administrative [Member]
Other Commitments [Line Items]
Operating lease cost				$ 122	$ 122	$ 365	$ 365
Non-Exclusive License Agreement | Enteris Biopharma, Inc. [Member]
Other Commitments [Line Items]
Upfront fee	$ 8,000
Upfront fee payment, cash	4,000
Upfront fee payment, stock	$ 4,000
MSA [Member] | Patheon and Patheon Manufacturing Services LLC [Member]
Other Commitments [Line Items]
Number of related product agreements | agreement			2
API Commercial Supply Agreement - PPL [Member]
Other Commitments [Line Items]
Agreement renewal term		5 years