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Stock-Based Compensation - Summary of Stock Option Activity (Detail) - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of Options, Outstanding, Ending Balance 7,654,523 5,974,549 7,654,523 5,974,549
2014 Equity Incentive Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of Options, Outstanding, Beginning Balance     6,512,280  
Number of Options, Granted 437,500 30,000 1,739,919 819,250
Number of Options, Exercised     (46,277)  
Number of Options, Forfeited     (356,819)  
Number of Options, Expired     (194,580)  
Number of Options, Outstanding, Ending Balance 7,654,523   7,654,523  
Number of Options, Options exercisable 4,764,271   4,764,271  
Weighted-Average Exercise Price, Outstanding, Beginning Balance     $ 15.58  
Weighted-Average Exercise Price, Granted     10.28  
Weighted-Average Exercise Price, Exercised     6.26  
Weighted-Average Exercise Price, Forfeited     14.50  
Weighted-Average Exercise Price, Expired     16.21  
Weighted-Average Exercise Price, Outstanding, Ending Balance $ 14.47   $ 14.47