Commitments and Contingencies - Additional Information (Detail) $ in Thousands		1 Months Ended			3 Months Ended		6 Months Ended
	Aug. 20, 2019 USD ($)	Jul. 31, 2021	Jun. 30, 2021 USD ($)	Jul. 31, 2019 agreement	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)
Other Commitments [Line Items]
Lease term			2 years 6 months		1 year 6 months	2 years 6 months	1 year 6 months	2 years 6 months
Operating lease liabilities					$ 2,818		$ 2,818
Enteris Biopharma, Inc. [Member]
Other Commitments [Line Items]
Payment of milestone payment			$ 10,000		0	$ 10,000	0	$ 10,000
Payments for Royalties					0		0
Stamford Operating Lease and New Stamford Lease [Member]
Other Commitments [Line Items]
Operating lease cost					406	406	812	812
Stamford Operating Lease and New Stamford Lease [Member] | Research and Development [Member]
Other Commitments [Line Items]
Operating lease cost					284	284	568	568
Stamford Operating Lease and New Stamford Lease [Member] | General and Administrative [Member]
Other Commitments [Line Items]
Operating lease cost					$ 122	$ 122	$ 244	$ 244
Non-Exclusive License Agreement | Enteris Biopharma, Inc. [Member]
Other Commitments [Line Items]
Upfront fee	$ 8,000
Upfront fee payment, cash	4,000
Upfront fee payment, stock	$ 4,000
MSA [Member] | Patheon and Patheon Manufacturing Services LLC [Member]
Other Commitments [Line Items]
Number of related product agreements | agreement				2
API Commercial Supply Agreement - PPL [Member]
Other Commitments [Line Items]
Agreement renewal term		5 years