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Stock-Based Compensation - Summary of Stock Option Activity (Detail) - $ / shares
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of Options, Outstanding, Ending Balance 7,419,027 5,995,223 7,419,027 5,995,223
2014 Equity Incentive Plan [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Number of Options, Outstanding, Beginning Balance     6,512,280  
Number of Options, Granted 324,981 116,050 1,302,419 789,250
Number of Options, Exercised     (30,470)  
Number of Options, Forfeited     (293,143)  
Number of Options, Expired     (72,059)  
Number of Options, Outstanding, Ending Balance 7,419,027   7,419,027  
Number of Options, Options exercisable 4,694,573   4,694,573  
Weighted-Average Exercise Price, Outstanding, Beginning Balance     $ 15.58  
Weighted-Average Exercise Price, Granted     10.21  
Weighted-Average Exercise Price, Exercised     6.09  
Weighted-Average Exercise Price, Forfeited     14.85  
Weighted-Average Exercise Price, Expired     19.42  
Weighted-Average Exercise Price, Outstanding, Ending Balance $ 14.67   $ 14.67