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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Operating activities    
Net loss $ (27,749) $ (23,301)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 5,704 4,132
Depreciation and amortization 63 63
Amortization expense component of lease expense 344 316
Amortization of available-for-sale marketable securities, net 292 194
Realized gain on sale of available-for-sale marketable securities   (39)
Realized gain on sale of property and equipment   (70)
Changes in operating assets and liabilities:    
Accounts receivable - related party (2,496)  
Inventory, net 677  
Other receivables 17 (1,687)
Prepaid expenses (2,594) (942)
Accounts payable and accrued expenses 640 (2,001)
Operating lease liabilities (423) (386)
Net cash used in operating activities (25,525) (23,721)
Investing activities    
Proceeds from maturities of available-for-sale marketable securities 44,000 27,655
Proceeds from redemptions of available-for-sale marketable securities, at par   2,100
Proceeds from sale of available-for-sale marketable securities 0 8,029
Purchases of available-for-sale marketable securities (10,526) (23,985)
Purchases of property and equipment (43)  
Proceeds from sale of property and equipment   70
Net cash provided by investing activities 33,431 13,869
Financing activities    
Proceeds from the exercise of stock options 3 688
Net cash provided by financing activities 3 688
Net increase (decrease) in cash, cash equivalents and restricted cash 7,909 (9,164)
Cash, cash equivalents and restricted cash at beginning of period 13,861 32,091
Cash, cash equivalents and restricted cash at end of period $ 21,770 $ 22,927