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Stock-Based Compensation - Summary of Assumptions Used in Black-Scholes Option Pricing Model (Detail)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Risk-free interest rate, minimum 0.66% 0.35% 1.55%
Risk-free interest rate, maximum 1.41% 1.57% 2.62%
Expected volatility, minimum 71.60% 71.80% 71.10%
Expected volatility, maximum 83.50% 74.80% 75.20%
Expected dividend yield 0.00% 0.00% 0.00%
Employee and Board of Directors Options [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected life of options (in years) 6 years 3 months 6 years 3 months 6 years 3 months