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Property and Equipment, net - Property and Equipment, net (Detail) - USD ($)
$ in Thousands
Dec. 31, 2021
Dec. 31, 2020
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 1,792 $ 2,381
Less accumulated depreciation and amortization 1,161 1,541
Property, Plant and Equipment, net, Total 631 840
Computer and Office Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 239 211
Laboratory Equipment [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross   628
Furniture and Fixtures [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 330 330
Leasehold Improvements [Member]    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 1,223 $ 1,212